Table 1.

Effects of BIBF1000 and BIBF1120 on the colony formation of myeloid cell lines (IC50 values for colony formation)

Cell lineIC50 (nmol/L)
BIBF1000BIBF1120
HL-60500>1,000
Kasumi-188
K 562600700
Meg 01500400
Moe 780>1,000
Mono-Mac-1840
NB-4900100
OCI-AML-2700>1,000
OCI-AML-5500400
TF-1>1,000>1,000
UT-7800800
32D400400
32D-FLT3-ITD>1,000>1,000
32D-FLT3-WT400350
  • NOTE: IC50 values were taken from more than two experiments.