Cancer genes analyzed
| Gene symbol | Gene name | National Center for Biotechnology Information gene ID | Likely oncogenic mutations* |
|---|---|---|---|
| APC | Adenomatous polyposis coli | 324 | 8 |
| BRAF | v-raf murine sarcoma viral oncogene homologue B1 | 673 | 10 |
| BRCA1 | Familial breast/ovarian cancer gene 1 | 672 | 0 |
| BRCA2 | Familial breast/ovarian cancer gene 2 | 675 | 0 |
| CDKN2A | Cyclin-dependent kinase inhibitor 2A, p16 | 1029 | 33 |
| CTNNB1 | Catenin (cadherin associated protein) β1 | 1499 | 1 |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homologue 2 | 2064 | 0 |
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homologue | 3265 | 1 |
| EGFR | Epidermal growth factor receptor | 1956 | 0 |
| FLT3 | fms-related tyrosine kinase 3 | 2322 | 0 |
| KIT | v-KIT Hardy-Zuckerman 4 feline sarcoma viral oncogene homologue | 3815 | 0 |
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologue | 3845 | 11 |
| MAP2K4 | Mitogen-activated protein kinase kinase 4 | 6416 | 0 |
| MET | met proto-oncogene | 4233 | 0 |
| NRAS | Neuroblastoma RAS viral (v-ras) oncogene homologue | 4893 | 3 |
| PDGFRA | Platelet-derived growth factor receptor, α polypeptide | 5156 | 0 |
| PIK3CA | Phosphoinositide-3-kinase, catalytic, α polypeptide | 5290 | 7 |
| PTEN | Phosphatase and tensin homologue | 5728 | 11 |
| RB1 | Retinoblastoma 1 | 5925 | 3 |
| RET | ret proto-oncogene | 5979 | 0 |
| SMAD4 | SMAD, mothers against DPP homologue 4 (MADH4) | 4089 | 2 |
| STK11 | Serine/threonine kinase 11/LKB1 (Peutz-Jehgers syndrome) | 6794 | 4 |
| TP53 | Tumor protein p53 (Li-Fraumeni syndrome) | 7157 | 41 |
| VHL | von Hippel-Lindau tumor suppressor | 7428 | 2 |
↵* Mutations seen in common ancestor lines counted once.