Table 1.

Characterization of the EpoB480 cell line

A549
EpoB40
EpoB480
IC50 ratio
IC50, nmol/LIC50, nmol/L (fold)IC50, nmol/L (fold)EpoB480/EpoB40
EpoB1.06 ± 0.11101.03 ± 4.30 (95)942.00 ± 47.78 (889)9
Taxol3.30 ± 0.5271.88 ± 16.29 (22)803.55 ± 13.88 (244)11
VBL3.09 ± 0.311.69 ± 0.63 (0.5)1.91* ± 0.20 (0.6)
  • NOTE: IC50 values were determined after 72 hours of incubation with the indicated drugs and were expressed as mean ± SE (n = 3).

    Abbreviation: VBL, vinblastine.

  • * IC50 determined in the presence of 125 nmol/L EpoB.