Table 4.

Hallmarks of cancer for DLBCL: DLBCL vs peripheral blood B cells and lymph node

Gene nameFold ΔDefinitions
Proliferation
    IGFBP7107IGF-I-binding protein
    CD2098Tetraspanin
    CD7283Type II membrane protein C-type lectin
    CRIP167Zinc finger motif, group II LIM protein family
    RAB1323GTPase
Tumor suppressors
    GPNMB97Transmembrane glycoprotein
    CD6390Tetraspanin
    BTG267B-cell translocation gene 2
    RARRES364Retinoic acid receptor response gene 3
Invasion and metastasis
    LUM67Lumican, ECM
    FN159Fibronectin, ECM
    MMP140MMP, ECM
    COL6A324Collagen, ECM
Unlimited replication
    CCR182Chemokine receptor, inflammation
    CCL514Chemokine ligand, inflammation
Angiogenesis
    VEGF65Vascular endothelial growth factor
    PDGF-AA14Platelet-derived growth factor
    PDGFR-β10Platelet-derived growth factor receptor
    FGF136Fibroblast growth factor
Apoptosis
    CD14141Lipopolysaccharide receptor, glycosylphosphatidylinisotol anchor
    BCL2A1107B-cell lymphoma 2