Table 4.

Results of scoring cell death morphologies of Diff-Quik-stained cytospins (n≥500 cells)

Cell lineDose (nmol/L), docetaxel*NormalNormal mitoticNonapoptotic death
Apoptosis
Aberrant mitosesMultinucleateOther nonapoptotic cell deathTotal
MCF-10A098.81.20.00.00.00.00.0
1076.00.05.717.90.223.80.1
10085.00.02.29.03.414.60.4
MCF-7097.71.01.10.00.21.30.0
1081.60.56.16.15.617.80.0
10043.50.710.735.59.655.80.0
MDA-mb-231094.02.30.90.72.03.60.0
1061.40.69.325.62.937.80.1
10019.30.411.366.42.580.20.2
  • * 0 nmol/L dose contained diluted docetaxel carrier.

  • Other nonapoptotic cell death includes vacuolated nuclei and nonapoptotic darkly stained nuclei.