Table 1.

New inhibitors of the human Eg5 ATPase activity

NameNSC No.Structure
1,6,7,1′,6′,7′-Hexahydroxy-5,5′-diisopropyl-3,3′-dimethyl-[2,2′-binaphthalene]-8,8′-dicarboxaldehyde (gossypol)56817Embedded Image
2-{[2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-1-piperazinyl)ethyl]amino}-ethanol trihydrochloride169676Embedded Image
S-trityl-l-cysteine83265Embedded Image
No structure no name available in chemical databases (K6Mo18O62P2)622124K6Mo18O62P2
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride (flexeril)78206Embedded Image
2,3,4,5-Tetrabromo-6-(3,6-dihydroxy-9H-xanthen-9-yl)-benzoic acid119889Embedded Image
1,1,2,2-Tetra(3,5-dichloro-4-hydroxyphenyl)ethane172033Embedded Image
10-Carboxy-1,2,3,4,5,6,7,8,13,13,14,14-dodecachloro-1,4,4a,4b,5,8,8a,8b-octahydro-11-sulfo-1,4:5,8-dimethanotriphenylene270718Embedded Image
2,2′-Dithiobis-(8-quinolinol)125034Embedded Image
8-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-8-azabicyclo[3.2.1]octane-3-ol, compound with ethanesulfonic acid59349Embedded Image