Table 2.

NCI-sponsored clinical trials of 17AAG

Phase I Pediatric Single Agent
Trial Site
Hematopoetic and solid tumorsPOIETIC Consortium
Hematopoetic and solid tumors
COG Consortium
Phase II Adult Single Agent
Trial Site
MelanomaRoyal Marsden (United Kingdom), Memorial Sloan-Kettering Cancer Center
Renal cellMemorial Sloan-Kettering Cancer Center, NCI
OvarianMayo Clinic
ThyroidMayo Clinic with Washington University
BreastWayne State University
MastocytosisNCI with Mayo Clinic
Prostate (hormone refractory)
Wayne State University
Phase Ib Adult Combination Regimens
Combination Agent
Trial Site
Gemcitabine/cis-diamminedichloroplatinumMayo Clinic
DocetaxelMemorial Sloan-Kettering Cancer Center
PaclitaxelPittsburgh University
ImatanibWayne State University
RituximabOhio State University
AraC/DaunomycinMayo Clinic
IrinotecanMemorial Sloan-Kettering Cancer Center