Table 1.

Hsp90 inhibitors

Site of ActionClassMembers
NH2-terminal ATPaseBenzoquinoneGeldanamycin
AnsamycinHerbimycin A
Macbecins I and II
17AAG
17-(desmethoxy),17-dimethylaminoethylamino geldanamycin
MacrolideRadicicol
Monocillin I
KF58333 (radicicol oxime derivative)
Purine scaffoldPU3
PU24FC1
PyrazoleCCT018159
COOH-terminal ATPaseCoumarin antibioticNovobiocin
Cross-linkerCisplatin
OtherHistone deacetylase inhibitorDepsipeptide
Suberoylanilide hydroxamic acid