Table 1.

Effects of PEITC and PITC on PC-3 cell cycle distribution

Treatment% Cells
Sub-G0-G1G0-G1SG2-M
Control (DMSO)4 ± 0.556 ± 115 ± 0.519 ± 0.5
5 μm PEITC14 ± 3*42 ± 3*14 ± 0.531 ± 1*
10 μm PEITC16 ± 1*34 ± 5*13 ± 136 ± 4*
5 μm PITC4 ± 0.559 ± 114 ± 0.520 ± 1
10 μm PITC4 ± 0.556 ± 0.515 ± 0.521 ± 0.5
  • Note: Cells were treated with DMSO (control) or different concentrations of PEITC or PITC for 24 h at 37°C. Both floating and attached cells were collected and processed for analysis of cell cycle distribution by flow cytometry following staining with propidium iodide. Data are means ± SE (n = 3).

  • * ,P < 0.05, significantly different compared with control (one-way ANOVA).