Cisplatin | Carboplatin | Oxaliplatin | Doxorubicin | Vinblastine | ||||||
---|---|---|---|---|---|---|---|---|---|---|

SCLC | ||||||||||

Vector | 21.8 ± 0.9 | 80.3 ± 7.6 | 24.5 ± 3.5 | 0.30 ± 0.06 | 11.1 ± 0.9 | |||||

WT | 12.3 ± 2.5* | 33.6 ± 11* | 15.5 ± 5.9^{†} | 0.37 ± 0.07 | 10.8 ± 2.0 | |||||

SR2 | ||||||||||

Vector | 110.6 ± 15^{‡} | 109.7 ± 15^{‡} | 18.8 ± 5.7 | 0.23 ± 0.04 | 9.3 ± 3.2 | |||||

WT | 39.7 ± 3.7^{§} | 65.3 ± 12^{§} | 21.1 ± 14 | 0.32 ± 0.05 | 10.7 ± 3.3 | |||||

δN | 131.8 ± 11 | 113.3 ± 5.9 | 19.4 ± 5.8 | 0.24 ± 0.06 | 9.3 ± 3.9 | |||||

δC | 35.2 ± 13^{§} | 71.5 ± 6.6^{§} | 20.4 ± 6.5 | 0.23 ± 0.08 | 12.1 ± 1.3 |

NOTE: Data are expressed as means ± SD of triplicate measurements from three independent experiments.

↵*

*P*< 0.01, significantly different from the results of SCLC vector (Student's*t*test).↵†

*P*< 0.05, significantly different from the results of SCLC vector (Student's*t*test).↵‡

*P*< 0.01, significantly different from the results of SCLC vector (Student's*t*test).↵§

*P*< 0.01, significantly different from the results of SR2 vector (Student's*t*test).