Table 3

Genes discriminating between ALL of T- and B-lineage

Weightαup(+)/down(−) in T vs. BClone IDGene
4.5159502562279Immunoglobulin heavy constant μ
3.720890.0024+247831ESTsa
3.355460246748Bruton agammaglobulinemia tyrosine kinase
3.162780241066Homo sapiens cDNA: FLJ21028 fis, clone CAE07155
3.103260+2143529T-cell receptor-interacting molecule
3.053680845311DKFZP566F084 protein
2.937120.0024+377560CD3D antigen, δ polypeptide (TiT3 complex)
2.8017202409188B-cell linker protein
2.7804902333826MD-1, RP105-associated
2.665960110281Syntaxin 7
2.6428701527066Homo sapiens early B-cell transcription factor mRNA, partial cds
2.6234502369226Eukaryotic translation initiation factor 2, subunit 3 (γ, 52 kDa)
2.514440214441Immunoglobulin heavy constant μ
2.458230+2871658T-cell activation, increased late expression
2.412460.0021+452023Ubiquitin associated and SH3 domain containing, A
2.344410366945Spleen focus forming virus proviral integration oncogene spi1
2.343090813390ESTs, weakly similar to KIAA0766 [H. sapiens]
2.339760+462431Ubiquitin-specific protease 20
2.328470+448068Hypothetical protein FLJ10204
2.299140825687Early B-cell factor
2.289690+205239Protein kinase C, θ
2.28310+2164126Protein kinase C, θ
2.26390+1543346Transketolase-like 1
2.206740705274Diacylglycerol kinase, δ (130 kDa)
2.198520613251DEAD-box protein abstrakt
2.106780.0024+2018154Electron-transfer-flavoprotein, β polypeptide
2.073040.0023+840444Homo sapiens cDNA: FLJ22439 fis, clone HRC09236
2.070920878259Peroxiredoxin 1
2.070010505882Hypothetical protein FLJ20550
2.0621402507433Suppressor of clear, C. elegans, homologue of
2.041420+208531Hypothetical protein FLJ20551
2.035370.0024472103Suppressor of clear, C. elegans, homologue of
2.028032229Homo sapiens cDNA: FLJ23227 fis, clone CAE00645, highly similar to AF052138 Homo sapiens clone 23718 mRNA sequence
2.02090129613Paired box gene 5 (B-cell lineage-specific activator protein)
2.017730.00241561558ESTs, highly similar to ITF2_HUMAN TRANSCRIPTION FACTOR 4 [H. sapiens]
1.989060.0023+1869186CGI-39 protein; cell death-regulatory protein GRIM19
1.945720+725746Signal transducer and activator of transcription 3 (acute-phase response factor)
1.9336401635695KIAA1080 protein; Golgi-associated, γ-adaptin ear containing, ARF-binding protein 2
1.913360753633KIAA0854 protein
1.91190.0023+462431Ubiquitin-specific protease 20
1.91076085624Complement component 4 binding protein, α
1.903230.0021810740Immunoglobulin λ locus
1.8992802548338Diacylglycerol kinase,δ (130 kDa)
1.886140.00262215191KIAA1032 protein
1.870440.0024+1636257Dynactin 3 (p22)
1.865140.0019+810859Natural killer cell transcript 4
1.842920.0024+357626Fumarylacetoacetase
1.840840+2281706IL-2-inducible T-cell kinase
1.83353042214Spleen tyrosine kinase
1.825430.0022115281CD79A antigen (immunoglobulin-associated α)
  • a EST, expressed sequence tag; ARF, ADP ribosylation factor; IL, interleukin.