Table 1.

Selected biochemical IC50 data (in μm) for the Src inhibitors used in these studies

Data for PP1 and PP2 are included for comparison. Enzymatic assays were performed as described previously (21).
KinaseSU11333SU11336SU12470CGP77675PP1PP2
Src0.10.070.010.020.2<0.01
Yes0.020.01<0.0090.20.010.03
Flk-11.10.52.01.20.10.8
PDGFRβa3.34.02.00.011.30.6
Met4.01.0>20>209.59.6
  • a PDGFRβ, PDGF receptor β.