Table 1

Cell cycle analysis of glioblastoma cell lines with and without flavopiridol treatment

Time (h)PhaseA172 (wt)a
U87MG (wt)
T98G (mu)
U118MG (mu)
ControlFlavoControlFlavoControlFlavoControlFlavo
0Sub-G13.462.54.724.319.615.058.653.24
G0-G167.7870.5240.2343.0948.649.1675.0675.25
S26.0924.7857.4555.1146.0944.6615.9415.36
G2-M5.654.692.321.85.36.1899.38
24Sub-G12.9215.431.758.915.613.4510.9315.45
G0-G166.863.0757.6843.0147.8739.3848.658.18
S23.2425.0127.3812.2843.5316.331.8128.07
G2-M9.9511.9214.9444.718.644.3219.5913.76
48Sub-G12.8628.512.268.622.3223.597.3412.34
G0-G172.4862.6877.7744.1454.6238.7962.2554.18
S18.3123.4113.837.7636.1616.7422.3825.67
G2-M9.2113.928.448.19.2245.0715.3620.14
72Sub-G13.8434.263.2522.183.0634.51525.38
G0-G159.9570.1784.3246.36442.8361.6257.54
S30.9216.2212.0710.4428.7620.9725.2325.22
G2-M9.1313.6127.64277.2536.213.1317.24
  • a wt, wild-type p53; mu, mutant p53; flavo, flavopiridol-treated cells.