Table 1

Summary of inhibitors of ion transport used in the present study

CNCnMCT-1, MCT-4Reduces pHi in vitro(16, 18, 38, 58, 59)
DBDSMCT-1, MCT-4Binds irreversibly, is a DIDS analogue, no data in vivo(59)
DIDSCl/HCO3 exchanger at 0.2 mm: has been reported to inhibit MCT-1, MCT-4 at 2 mmBinds irreversibly to the Cl/HCO3 exchanger(13, 14)
Cariporide mesilate(HOE642)NHE-1Water soluble(12)