Table 2.

Effects of sulfonamide antitumor agents on cell cycle progression and tubulin polymerization

FACS analyses were performed three times using propidium iodide staining to quantitate the DNA content. Mitotic index represents the percentage of mitotic cells under a microscope. Assembly of microtubules was evaluated turbidimetrically at 350 nm 30 min after the reaction mixture was warmed from 4 to 37°C. The experiments were carried out three times with each test compound.

Table 2.