Table 1

Human tumor specimens, cell lines, and xenografts used in this study

Specimen typeNumber
No prior paclitaxel exposure (n = 49)
 Ovarian carcinoma clinical specimens16
 Ovarian carcinoma cell lines16
 Lung carcinoma clinical specimens17
Paclitaxel resistant (n = 30)
 Ovarian carcinoma clinical specimens9
 Ovarian carcinoma lines selected with paclitaxel6
 Ovarian carcinoma lines selected with paclitaxel and PSC 8333
 Ovarian carcinoma xenografts selected with paclitaxel12