Table 1

MVA-m5T4 does alter fertility

A. Inoculation with MVA-m5T4 does not effect fertility of C57BL/6 mice^a
	10 day study					30 day study	60 day study
		MVA- m5T4	MVA- LacZ	PBS	MVA- m5T4	MVA- m5T4
No. of pregnancies	4/5	4/5	3/5	4/5	5/5
No. live births	24	30	18	22	33
Average litter size	6	7.5	6	5.5	6.6

B. Inoculation with MVA-m5T4 does not effect fertility of BALB/c mice or the health of their pups^b
	10 day study					45 day study
		MVA-m5T4	MVA-LacZ	PBS	MVA-m5T4
No. of pregnancies	5/5	4/5	4/5	4/4
No. live births	30	23	22	24
Average litter size	6	5.75	5.5	6
Ratio F:M	13:11	14:5	11:11	15:9
Average weights	10.4 g	11.2 g	10.1 g	11.4 g

↵^a C57BL/6 mice were inoculated with MVA-m5T4, MAV-LacZ, or PBS at 0, 21, and 42 days; the mice were then mated at day 10 after last inoculation. MVA-m5T4 groups were also mated at days 30 and 60 after last inoculation.
↵^b BALB/c mice were inoculated with MVA-m5T4, MAV-LacZ, or PBS at 0, 21, and 42 days; the mice were then mated at day 10 after last inoculation. An MVA-m5T4 group was also mated at 45 days after last inoculation.