Table 3

4-HPR increased NOS expression in breast cancer cells

Intensitya
Percentageb
NOSIINOSIIINOSIINOSIII
Untreated+
4-HPR (1 μm)++++++
4-HPR (2.5 μm)+++++++++++
IFN-γ (50 IU/ml)
IFN-γ + 4-HPRc+++++++
TAM (1 μm)+++
TAM + 4-HPRd++++
  • a Intensity of NOS immunostainings: −, none; +, light; ++, moderate; +++, intense.

  • b Percentage of NOS immunostainings: −, <5%; +, 5–25%; ++, 26–50%; +++, 51–75%; ++++, 76–95%; +++++, >95%.

  • c 50 IU/ml IFN-γ and 1 μm 4-HPR were used.

  • d 1 μm TAM and 1 μm 4-HPR were used.