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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics

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Research Article

U3-1402, a novel HER3-targeting antibody-drug conjugate, for the treatment of Colorectal Cancer

Shigehiro Koganemaru, Yasutoshi Kuboki, Yoshikatsu Koga, Takashi Kojima, Mayumi Yamauchi, Naoyuki Maeda, Takashi Kagari, Kenji Hirotani, Masahiro Yasunaga, Yasuhiro Matsumura and Toshihiko Doi
Shigehiro Koganemaru
Department of Experimental Therapeutics, National Cancer Center Hospital East
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Yasutoshi Kuboki
Department of Experimental Therapeutics, National Cancer Center Hospital East
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  • For correspondence: ykuboki@east.ncc.go.jp
Yoshikatsu Koga
Division of Developmental Therapeutics, National Cancer Center Hospital East
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Takashi Kojima
Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East
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Mayumi Yamauchi
Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East
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Naoyuki Maeda
Biomarker & Translational Research Department, Daiichi Sankyo Co., Ltd.
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Takashi Kagari
Oncology Research Laboratories I, Daiichi Sankyo Co., Ltd.
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Kenji Hirotani
Oncology Clinical Development Department, DAIICHI SANKYO CO.,LTD.
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Masahiro Yasunaga
Division of Developmental Therapeutics, National Cancer Center Hospital East
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  • ORCID record for Masahiro Yasunaga
Yasuhiro Matsumura
Division of Developmental Therapeutics, National Cancer Center Hospital East
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Toshihiko Doi
Department of Experimental Therapeutics, National Cancer Center Hospital East
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DOI: 10.1158/1535-7163.MCT-19-0452
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ARTICLE USAGE: August 2019 to December 2019

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Cited By

Article Information

DOI 
https://doi.org/10.1158/1535-7163.MCT-19-0452
PubMed 
31395690

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received April 28, 2019
  • Revision received June 28, 2019
  • Accepted August 2, 2019
  • Published first August 8, 2019.

Article Versions

  • You are currently viewing a Previous version of this article (August 8, 2019 - 06:06).
  • View the most recent version of this article
Copyright & Usage 
Copyright ©2019, American Association for Cancer Research.

Author Information

  1. Shigehiro Koganemaru1,
  2. Yasutoshi Kuboki1,*,
  3. Yoshikatsu Koga2,
  4. Takashi Kojima3,
  5. Mayumi Yamauchi3,
  6. Naoyuki Maeda4,
  7. Takashi Kagari5,
  8. Kenji Hirotani6,
  9. Masahiro Yasunaga2,
  10. Yasuhiro Matsumura2, and
  11. Toshihiko Doi1
  1. 1Department of Experimental Therapeutics, National Cancer Center Hospital East
  2. 2Division of Developmental Therapeutics, National Cancer Center Hospital East
  3. 3Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East
  4. 4Biomarker & Translational Research Department, Daiichi Sankyo Co., Ltd.
  5. 5Oncology Research Laboratories I, Daiichi Sankyo Co., Ltd.
  6. 6Oncology Clinical Development Department, DAIICHI SANKYO CO.,LTD.
  1. ↵* Corresponding Author:
    Yasutoshi Kuboki, Department of Experimental Therapeutics, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. E-mail: ykuboki{at}east.ncc.go.jp
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Published OnlineFirst August 8, 2019
doi: 10.1158/1535-7163.MCT-19-0452

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U3-1402, a novel HER3-targeting antibody-drug conjugate, for the treatment of Colorectal Cancer
Shigehiro Koganemaru, Yasutoshi Kuboki, Yoshikatsu Koga, Takashi Kojima, Mayumi Yamauchi, Naoyuki Maeda, Takashi Kagari, Kenji Hirotani, Masahiro Yasunaga, Yasuhiro Matsumura and Toshihiko Doi
Mol Cancer Ther August 8 2019 DOI: 10.1158/1535-7163.MCT-19-0452

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U3-1402, a novel HER3-targeting antibody-drug conjugate, for the treatment of Colorectal Cancer
Shigehiro Koganemaru, Yasutoshi Kuboki, Yoshikatsu Koga, Takashi Kojima, Mayumi Yamauchi, Naoyuki Maeda, Takashi Kagari, Kenji Hirotani, Masahiro Yasunaga, Yasuhiro Matsumura and Toshihiko Doi
Mol Cancer Ther August 8 2019 DOI: 10.1158/1535-7163.MCT-19-0452
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Molecular Cancer Therapeutics
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