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More articles from Therapeutic Discovery

Discovery and Evaluation of Inhibitors of Human Ceramidase
Jeremiah M. Draper, Zuping Xia, Ryan A. Smith, Yan Zhuang, Wenxue Wang, Charles D. Smith

Molecular Cancer Therapeutics Nov 2011, 10 (11) 2052-2061; DOI: 10.1158/1535-7163.MCT-11-0365
Digitoxin-Induced Cytotoxicity in Cancer Cells Is Mediated through Distinct Kinase and Interferon Signaling Networks
Ioannis Prassas, George S. Karagiannis, Ihor Batruch, Apostolos Dimitromanolakis, Alessandro Datti, Eleftherios P. Diamandis

Molecular Cancer Therapeutics Nov 2011, 10 (11) 2083-2093; DOI: 10.1158/1535-7163.MCT-11-0421
Targeting the Intracellular MUC1 C-terminal Domain Inhibits Proliferation and Estrogen Receptor Transcriptional Activity in Lung Adenocarcinoma Cells
Carolyn M. Klinge, Brandie N. Radde, Yoannis Imbert-Fernandez, Yun Teng, Margarita M. Ivanova, Sabra M. Abner, Alexandra L. Martin

Molecular Cancer Therapeutics Nov 2011, 10 (11) 2062-2071; DOI: 10.1158/1535-7163.MCT-11-0381
Genomic Profiling in CEPH Cell Lines Distinguishes between the Camptothecins and Indenoisoquinolines
Venita Gresham Watson, Nicholas E. Hardison, Tyndall Harris, Alison Motsinger-Reif, Howard L. McLeod

Molecular Cancer Therapeutics Oct 2011, 10 (10) 1839-1845; DOI: 10.1158/1535-7163.MCT-10-0872
A Molecular Screening Approach to Identify and Characterize Inhibitors of Glioblastoma Stem Cells
Koppany Visnyei, Hideyuki Onodera, Robert Damoiseaux, Kuniyasu Saigusa, Syuzanna Petrosyan, David De Vries, Denise Ferrari, Jonathan Saxe, Eduard H. Panosyan, Michael Masterman-Smith, Jack Mottahedeh, Kenneth A. Bradley, Jing Huang, Chiara Sabatti, Ichiro Nakano, Harley I. Kornblum

Molecular Cancer Therapeutics Oct 2011, 10 (10) 1818-1828; DOI: 10.1158/1535-7163.MCT-11-0268
Prioritizing Candidate Disease miRNAs by Topological Features in the miRNA Target–Dysregulated Network: Case Study of Prostate Cancer
Juan Xu, Chuan-Xing Li, Jun-Ying Lv, Yong-Sheng Li, Yun Xiao, Ting-Ting Shao, Xiao Huo, Xiang Li, Yan Zou, Qing-Lian Han, Xia Li, Li-Hua Wang, Huan Ren

Molecular Cancer Therapeutics Oct 2011, 10 (10) 1857-1866; DOI: 10.1158/1535-7163.MCT-11-0055
A Novel Kinase Inhibitor of FADD Phosphorylation Chemosensitizes through the Inhibition of NF-κB
Katrina A. Schinske, Shyam Nyati, Amjad P. Khan, Terence M. Williams, Timothy D. Johnson, Brian D. Ross, Ricardo Pérez Tomás, Alnawaz Rehemtulla

Molecular Cancer Therapeutics Oct 2011, 10 (10) 1807-1817; DOI: 10.1158/1535-7163.MCT-11-0362
Targeting Tumor-Initiating Cancer Cells with dCD133KDEL Shows Impressive Tumor Reductions in a Xenotransplant Model of Human Head and Neck Cancer
Nate N. Waldron, Dan S. Kaufman, Seunguk Oh, Zintis Inde, Melinda K. Hexum, John R. Ohlfest, Daniel A. Vallera

Molecular Cancer Therapeutics Oct 2011, 10 (10) 1829-1838; DOI: 10.1158/1535-7163.MCT-11-0206
An Integrated Chemical Biology Approach Identifies Specific Vulnerability of Ewing's Sarcoma to Combined Inhibition of Aurora Kinases A and B
Georg E. Winter, Uwe Rix, Andrej Lissat, Alexey Stukalov, Markus K. Müllner, Keiryn L. Bennett, Jacques Colinge, Sebastian M. Nijman, Stefan Kubicek, Heinrich Kovar, Udo Kontny, Giulio Superti-Furga

Molecular Cancer Therapeutics Oct 2011, 10 (10) 1846-1856; DOI: 10.1158/1535-7163.MCT-11-0100
Identification of a Natural Compound by Cell-Based Screening That Enhances Interferon Regulatory Factor-1 Activity and Causes Tumor Suppression
Jinbo Gao, Yujun Wang, Quanhua Xing, Jin Yan, Maheswari Senthil, Yasir Akmal, Claudia M. Kowolik, Julia Kang, David M. Lu, Ming Zhao, Zhixiu Lin, Christopher H.K. Cheng, M.L. Richard Yip, John H. Yim

Molecular Cancer Therapeutics Oct 2011, 10 (10) 1774-1783; DOI: 10.1158/1535-7163.MCT-11-0304

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