More articles from Therapeutic Agents: Biological

Abstract LB-B24: Targeting transcriptional addiction for the treatment of TSC
Mahsa zarei, Heng Du, Rachel E. Yan, Yubao Wang, Thingu Zhang, John M. Asara, David J. Kwiatkowski

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) LB-B24; DOI: 10.1158/1535-7163.TARG-17-LB-B24
Abstract B115: MORAb-202: a folate receptor alpha (FRA)-targeting antibody-drug conjugate, exhibiting targeted antitumor activity and bystander elimination of cancer-associated fibroblasts
Katherine A. Rybinski, Christopher Maddage, Xin Cheng, Earl Albone, Luigi Grasso, Keiji Furuuchi, Toshimitsu Uenaka

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B115; DOI: 10.1158/1535-7163.TARG-17-B115
Abstract B106: Antibody-drug conjugates targeted at human aspartyl (asparaginyl) β-hydroxylase
Kanam Malhotra, Susan Walker, Chen Fang, Karamveer Birthare, Michael S. Lebowitz, Steven Fuller, Muctarr Sesay, Hossein A. Ghanbari

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B106; DOI: 10.1158/1535-7163.TARG-17-B106
Abstract B104: A therapeutic antibody candidate against the broadly expressed Tn and STn carbohydrate cancer antigens
G Jonah Rainey, Ritsuko Sawada, Toni Jun, Aleksandra Marinkovic-Petrovic, Ayesha Kahn, Wolfgang Scholz, Paul W. Maffuid

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B104; DOI: 10.1158/1535-7163.TARG-17-B104
Abstract B108: Antitumor efficacy of EGFR antibody necitumumab and dual PI3K/mTOR inhibitor (LY3023414) in preclinical tumor models
Maxine A. Melchior, Xuemei Guo, Gregory P. Donoho, Philip W. Iversen, Thompson N. Doman, Manisha Brahmachary, Xueqian Gong, Gerald E. Hall, Jason R. Manro, Yung-mae M. Yao, Sean Buchanan, Tod Smeal, Michael D. Kalos, Ruslan D. Novosiadly

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B108; DOI: 10.1158/1535-7163.TARG-17-B108
Abstract B110: Brusatol-induced degradation of HIF-1α by inhibiting c-Myc causes colorectal cancer cell death under hypoxia
Eun-Taex Oh, Chan Woo Kim, Ha Gyeong Kim, Heon Joo Park

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B110; DOI: 10.1158/1535-7163.TARG-17-B110
Abstract B120: TAK-164, a GCC-targeted antibody-drug conjugate (ADC) for the treatment of colorectal cancers and other GI malignancies
Adnan O. Abu-Yousif, Bret M. Bannerman, Donna Cvet, Melissa Gallery, Michelle L. Ganno, Michael D. Smith, Katharine C. Lai, Thomas A. Keating, Jayaprakasam Bolleddula, Bradley Stringer, Mark G. Qian, Afrand Kamali, Kurt Eng, Secil Koseoglu, Cindy Q. Xia, O. Petter Veiby

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B120; DOI: 10.1158/1535-7163.TARG-17-B120
Abstract B105: ACTR707: a novel T-cell therapy for the treatment of relapsed or refractory CD20+ B cell lymphoma in combination with rituximab
Greg Motz, Kathleen Whiteman, John Shin, Tapasya Pai, Casey Judge, Anthony Barnitz, James Hemphill, James Kim, Ann Ranger, Heather Huet, Kathleen McGinness, Birgit Schultes, Geoffrey Hodge, Michael Vasconcelles, Seth Ettenberg

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B105; DOI: 10.1158/1535-7163.TARG-17-B105
Abstract LB-B25: Preliminary phase I data comparing HuMab-5B1 (MVT-5873), a monoclonal antibody targeting sLea, as a single agent and in combination with first line nab-paclitaxel and gemcitabine in patients with CA19-9 positive pancreatic cancer
Eileen Mary O'Reilly, Judy Sing-Zan Wang, Kenneth H. Yu, Maeve Aine Lowery, Anna M. Varghese, Johanna C. Bendell, Erkut Hasan Borazanci, Hayley Estrella, Kimberly Fowler, Mariella Hoskins, Stephanie Bussen, Teresa J. Melink, Christine M. Kearns, H Toni Jun, Paul W. Maffuid, John C. Gutheil, Todd Michael Bauer

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) LB-B25; DOI: 10.1158/1535-7163.TARG-17-LB-B25
Abstract B113: Development of a novel synthetic consensus DNA vaccine that targets multiple MAGE-A family members for anticancer immune therapy
Elizabeth K. Duperret, Aspen Trautz, Megan Paik, Charles Reed, Jian Yan, David B. Weiner

Molecular Cancer Therapeutics Jan 2018, 17 (1 Supplement) B113; DOI: 10.1158/1535-7163.TARG-17-B113

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