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Disruption of SND1-MTDH interaction by a high affinity peptide results in SND1 degradation and cytotoxicity to breast cancer cells in vitro and in vivo
Peng Li, Yunjiao He, Teng Chen, Kit-Ying Choy, Tsun Sing Chow, Iris L.K. Wong, Xinqing Yang, Wen-Qin Sun, Xiaochun Su, Tak-Hang CHAN, Larry M. C. Chow

Molecular Cancer Therapeutics Jan 2020, molcanther.0130.2020; DOI: 10.1158/1535-7163.MCT-20-0130
A Pilot Study of Galunisertib Plus Stereotactic Body Radiotherapy in Patients with Advanced Hepatocellular Carcinoma
Kim A Reiss, Max M Wattenberg, Nevena Damjanov, Elizabeth Prechtel Dunphy, Mona Jacobs-Small, M. Judy Lubas, James Robinson, Lisa Dicicco, Luis Garcia-Marcano, Michael A Giannone, Thomas B Karasic, Emma E Furth, Erica L Carpenter, Andrzej P Wojcieszynski, Robert H. Vonderheide, Gregory L. Beatty, Edgar Ben-Josef

Molecular Cancer Therapeutics Jan 2020, molcanther.0632.2020; DOI: 10.1158/1535-7163.MCT-20-0632
Combinatorial efficacy of olaparib with radiation and ATR inhibitor requires PARP1 protein in homologous recombination proficient pancreatic cancer
Leslie A Parsels, Carl G Engelke, Joshua Parsels, Sheryl A Flanagan, Qiang Zhang, Daria Tanska, Daniel R Wahl, Christine E Canman, Theodore S. Lawrence, Meredith A. Morgan

Molecular Cancer Therapeutics Jan 2020, molcanther.0365.2020; DOI: 10.1158/1535-7163.MCT-20-0365
IOX1 Suppresses Wnt Target Gene Transcription and Colorectal Cancer Tumorigenesis Through Inhibition of KDM3 Histone Demethylases
Rosalie G. Hoyle, Huiqun Wang, Yana Cen, Yan Zhang, Jiong Li

Molecular Cancer Therapeutics Jan 2020, molcanther.0328.2020; DOI: 10.1158/1535-7163.MCT-20-0328
TriTACs, a novel class of T cell-engaging protein constructs designed for the treatment of solid tumors
Richard J Austin, Bryan D Lemon, Wade H Aaron, Manasi Barath, Patricia A Culp, Robert B DuBridge, Luke B Evnin, Adrie Jones, Anand Panchal, Purbasa Patnaik, Vanitha Ramakrishnan, Sony S. Rocha, Pui Seto, Kenneth Sexton, Kathryn L Strobel, Russell Wall, Stephen Yu, Timothy Z. Yu, Che-Leung Law, Patrick A Baeuerle, Holger Wesche

Molecular Cancer Therapeutics Jan 2020, molcanther.0061.2020; DOI: 10.1158/1535-7163.MCT-20-0061
Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth.
Shauni Lien Geeraerts, Kim Rosalie Kampen, Gianmarco Rinaldi, Purvi Gupta, Melanie Planque, Nikolaos Louros, Elien Heylen, Kaat De Cremer, Katrijn De Brucker, Stijn Vereecke, Benno Verbelen, Pieter Vermeersch, Joost Schymkowitz, Frederic Rousseau, David Cassiman, Sarah-Maria Fendt, Arnout Voet, Bruno P.A. Cammue, Karin Thevissen, Kim De Keersmaecker

Molecular Cancer Therapeutics Jan 2020, molcanther.0480.2020; DOI: 10.1158/1535-7163.MCT-20-0480
Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer
Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Sean W Fanning, Jay S Hanspal, Ping Fan, Charles E Foulds, Yue Chen, Anna Malovannaya, Antrix Jain, Rui Xiong, Geoffrey L Greene, Debra A. Tonetti, Gregory R.J. Thatcher, V. Craig Jordan

Molecular Cancer Therapeutics Jan 2020, molcanther.0563.2020; DOI: 10.1158/1535-7163.MCT-20-0563
Circulating tumor cells and biomarker modulation with olaratumab monotherapy followed by olaratumab plus doxorubicin: phase 1b study in soft tissue sarcoma patients
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Molecular Cancer Therapeutics Jan 2020, molcanther.0441.2020; DOI: 10.1158/1535-7163.MCT-20-0441
PLK1 and NOTCH Positively Correlate in Melanoma and their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways
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Molecular Cancer Therapeutics Jan 2020, molcanther.0654.2020; DOI: 10.1158/1535-7163.MCT-20-0654
Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody Drug Conjugates to Increase In Vivo Efficacy
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Molecular Cancer Therapeutics Jan 2020, molcanther.0451.2020; DOI: 10.1158/1535-7163.MCT-20-0451

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