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Expression of the of the androgen receptor governs radiation resistance in a subset of glioblastomas vulnerable to anti-androgen therapy
Christian K. Werner, Uchechi J. Nna, Hanshi Sun, Kari Wilder-Romans, Joseph Dresser, Ayesha U. Kothari, Weihua Zhou, Yangyang Yao, Arvind Rao, Stefanie Stallard, Carl Koschmann, Tarik Bor, Waldemar Debinski, Alexander M. Hegedus, Meredith A. Morgan, Sriram venneti, Edwina Baskin-Bey, Daniel E. Spratt, Howard Colman, Jann N. Sarkaria, Arul M. Chinnaiyan, Joel R Eisner, Corey Speers, Theodore S. Lawrence, Roy E Strowd, Daniel R Wahl

Molecular Cancer Therapeutics Jan 2020, molcanther.0095.2020; DOI: 10.1158/1535-7163.MCT-20-0095
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-Derived Xenografts.
Adnan O Abu-Yousif, Donna Cvet, Melissa Gallery, Bret M Bannerman, Michelle L Ganno, Michael D Smith, Katharine C. Lai, Thomas A. Keating, Bradley Stringer, Afrand Kamali, Kurt Eng, Secil Koseoglu, Andy Zhu, Cindy Q. Xia, Melissa Saylor Landen, Maria Borland, Robbie Robertson, Jayaprakasam Bolleddula, Mark G Qian, Jennifer Fretland, O. Petter Veiby

Molecular Cancer Therapeutics Jan 2020, molcanther.1102.2019; DOI: 10.1158/1535-7163.MCT-19-1102
Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity in Vitro and in Vivo
Yamini M. Ohol, Michael T. Sun, Gene Cutler, Paul R Leger, Dennis X. Hu, Berenger Biannic, Payal Rana, Cynthia Cho, Scott Jacobson, Steve T Wong, Jerick Sanchez, Niket Shah, Deepa Pookot, Betty Abraham, Kyle Young, Silpa Suthram, Lisa A. Marshall, Delia Bradford, Nathan Kozon, Xinping Han, Akinori Okano, Jack Maung, Christophe Colas, Jacob Schwarz, David Wustrow, Dirk G Brockstedt, Paul D. Kassner

Molecular Cancer Therapeutics Jan 2020, molcanther.0184.2020; DOI: 10.1158/1535-7163.MCT-20-0184
Aurora A inhibitor TAS-119 enhances antitumor efficacy of taxanes in vitro and in vivo: preclinical studies as guidance for clinical development and trial design
Hiroshi Sootome, Akihiro Miura, Norio Masuko, Takamasa Suzuki, Yoshihiro Uto, Hiroshi Hirai

Molecular Cancer Therapeutics Jan 2020, molcanther.0036.2020; DOI: 10.1158/1535-7163.MCT-20-0036
PIM kinase inhibitors block the growth of primary T-cell acute lymphoblastic leukemia: Resistance pathways identified by network modeling analysis
James T Lim, Neha Singh, Libia A. Luevano, Valerie S. Calvert, Emanuel F Petricoin, David T. Teachey, Richard B Lock, Megha Padi, Andrew S. Kraft, Sathish Kumar Reddy Padi

Molecular Cancer Therapeutics Jan 2020, molcanther.0160.2020; DOI: 10.1158/1535-7163.MCT-20-0160
PF-06804103, a site-specific anti-HER2 antibody-drug conjugate for the treatment of HER2-expressing breast, gastric, and lung cancers
Edmund I. Graziani, Matthew Sung, Dangshe Ma, Bitha Narayanan, Kimberly Marquette, Sujiet Puthenveetil, L. Nathan Tumey, Jack Bikker, Jeffrey Casavant, Eric M Bennett, Manoj B Charati, Jonathan Golas, Christine Hosselet, Cynthia M Rohde, George Hu, magali guffroy, Hadi Falahatpisheh, Martin Finkelstein, Tracey Clark, Frank Barletta, Lioudmila Tchistiakova, Judy Lucas, Edward Rosfjord, Frank Loganzo, Christopher J. O'Donnell, Hans-Peter Gerber, Puja Sapra

Molecular Cancer Therapeutics Jan 2020, molcanther.0237.2020; DOI: 10.1158/1535-7163.MCT-20-0237
Amivantamab (JNJ-61186372), An Fc Enhanced EGFR/cMet Bispecific Antibody Induces Receptor Downmodulation And Anti-tumor Activity By Monocyte/Macrophage Trogocytosis
Smruthi Vijayaraghavan, Lorraine Lipfert, Kristen Chevalier, Barbara S Bushey, Benjamin Henley, Ryan Lenhart, Jocelyn Sendecki, Marilda Beqiri, Hillary J Millar, Kathryn Packman, Matthew V. Lorenzi, Sylvie Laquerre, Sheri L. Moores

Molecular Cancer Therapeutics Jan 2020, molcanther.0071.2020; DOI: 10.1158/1535-7163.MCT-20-0071
Polyamine Blocking Therapy Decreases Survival of Tumor-Infiltrating Immunosuppressive Myeloid Cells and Enhances the Anti-Tumor Efficacy of PD-1 Blockade
Susan K. Gilmour, Eric T Alexander, Kelsey Mariner, Julia Donnelly, Otto Phanstiel

Molecular Cancer Therapeutics Jan 2020, molcanther.1116.2019; DOI: 10.1158/1535-7163.MCT-19-1116
The discovery of SWI/SNF chromatin remodeling activity as a novel and targetable dependency in uveal melanoma
Florencia Rago, GiNell Elliott, AILING LI, Kathleen Sprouffske, Grainne Kerr, Aurore Desplat, Dorothee Abramowski, Julie T Chen, Ali Farsidjani, Kay X. Xiang, Geoffrey Bushold, Yun Feng, Matthew D. Shirley, Anka Bric, Anthony Vattay, Henrik Moebitz, Katsumasa Nakajima, Christopher D Adair, Simon Mathieu, Rukundo Ntaganda, Troy Smith, Julien P.N. Papillon, Audrey Kauffmann, David A. Ruddy, Hyo-eun C. Bhang, Deborah Castelletti, Zainab Jagani

Molecular Cancer Therapeutics Jan 2020, molcanther.1013.2019; DOI: 10.1158/1535-7163.MCT-19-1013
High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers
Paul Riviere, Aaron M. Goodman, Ryosuke Okamura, Donald A Barkauskas, Theresa J Whitchurch, Suzanna Lee, Noor Khalid, Rachel Collier, Manvita Marebiona, Garrett M. Frampton, David Fabrizio, Andrew B Sharabi, Shumei Kato, Razelle Kurzrock

Molecular Cancer Therapeutics Jan 2020, molcanther.0161.2020; DOI: 10.1158/1535-7163.MCT-20-0161

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