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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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More articles from Large Molecule Therapeutics

  • Interleukin-4 Receptor Inhibition Targeting Metastasis Independent of Macrophages
    Megan M. Cleary, Narendra Bharathy, Jinu Abraham, Erin R. Rudzinski, Joel E. Michalek, Charles Keller
    Molecular Cancer Therapeutics Apr 2021, DOI: 10.1158/1535-7163.MCT-20-0199
  • Preclinical Assessment of AMG 596, a Bispecific T-cell Engager (BiTE) Immunotherapy Targeting the Tumor-specific Antigen EGFRvIII
    Alexander Sternjak, Fei Lee, Oliver Thomas, Mercedesz Balazs, Joachim Wahl, Grit Lorenczewski, Ines Ullrich, Markus Muenz, Benno Rattel, Julie M. Bailis, Matthias Friedrich
    Molecular Cancer Therapeutics Feb 2021, DOI: 10.1158/1535-7163.MCT-20-0508
  • Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
    Amy A. Lo, Jennifer Johnston, Ji Li, Danielle Mandikian, Maria Hristopoulos, Robyn Clark, Dorothee Nickles, Wei-Ching Liang, Kathy Hötzel, Debra Dunlap, Thinh Pham, Hao Cai, Meric Ovacik, Daniel Bravo-Perez, Elaine Mai, Dionysos Slaga, Diego Ellerman, James Ziai, Klara Totpal, Genee Lee, C. Andrew Boswell, Jian Payandeh, Yan Wu, Teemu T. Junttila
    Molecular Cancer Therapeutics Apr 2021, 20 (4) 716-725; DOI: 10.1158/1535-7163.MCT-20-0490
  • Improved Antitumor Activity of the Fluoropyrimidine Polymer CF10 in Preclinical Colorectal Cancer Models through Distinct Mechanistic and Pharmacologic Properties
    William H. Gmeiner, Anthony Dominijanni, Alex O. Haber, Lais P. Ghiraldeli, David L. Caudell, Ralph D’Agostino, Boris C. Pasche, Thomas L. Smith, Zhiyong Deng, Sezgin Kiren, Chinnadurai Mani, Komaraiah Palle, Jonathan R. Brody
    Molecular Cancer Therapeutics Mar 2021, 20 (3) 553-563; DOI: 10.1158/1535-7163.MCT-20-0516
  • ABBV-085, Antibody–Drug Conjugate Targeting LRRC15, Is Effective in Osteosarcoma: A Report by the Pediatric Preclinical Testing Consortium
    Pooja Hingorani, Michael E. Roth, Yifei Wang, Wendong Zhang, Jonathan B. Gill, Douglas J. Harrison, Beverly Teicher, Stephen Erickson, Gregory Gatto, Malcolm A. Smith, Edward A. Kolb, Richard Gorlick
    Molecular Cancer Therapeutics Mar 2021, 20 (3) 535-540; DOI: 10.1158/1535-7163.MCT-20-0406
  • Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR
    Shenlan Mao, Raghothama Chaerkady, Wen Yu, Gina D’Angelo, Andrew Garcia, Hong Chen, Allison M. Barrett, Sandrina Phipps, Ryan Fleming, Sonja Hess, Jens-Oliver Koopmann, Nazzareno Dimasi, Susan Wilson, Kathryn Pugh, Kimberly Cook, Luke A. Masterson, Changshou Gao, Herren Wu, Ronald Herbst, Philip W. Howard, David A. Tice, Mark Cobbold, Jay Harper
    Molecular Cancer Therapeutics Mar 2021, 20 (3) 541-552; DOI: 10.1158/1535-7163.MCT-20-0351
  • Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12
    Nuruddeen D. Lewis, Chang Ling Sia, Katherine Kirwin, Sonya Haupt, Gauri Mahimkar, Tong Zi, Ke Xu, Kevin Dooley, Su Chul Jang, Bryan Choi, Adam Boutin, Andrew Grube, Christine McCoy, Jorge Sanchez-Salazar, Michael Doherty, Leonid Gaidukov, Scott Estes, Kyriakos D. Economides, Douglas E. Williams, Sriram Sathyanarayanan
    Molecular Cancer Therapeutics Mar 2021, 20 (3) 523-534; DOI: 10.1158/1535-7163.MCT-20-0484
  • HDP-101, an Anti-BCMA Antibody–Drug Conjugate, Safely Delivers Amanitin to Induce Cell Death in Proliferating and Resting Multiple Myeloma Cells
    Vianihuini Figueroa-Vazquez, Jonathan Ko, Christian Breunig, Anja Baumann, Nicola Giesen, Anikó Pálfi, Christoph Müller, Christian Lutz, Torsten Hechler, Michael Kulke, Carsten Müller-Tidow, Alwin Krämer, Hartmut Goldschmidt, Andreas Pahl, Marc S. Raab
    Molecular Cancer Therapeutics Feb 2021, 20 (2) 367-378; DOI: 10.1158/1535-7163.MCT-20-0287
  • Predicting Tumor Killing and T-Cell Activation by T-Cell Bispecific Antibodies as a Function of Target Expression: Combining In Vitro Experiments with Systems Modeling
    Arthur J. Van De Vyver, Tina Weinzierl, Miro J. Eigenmann, Nicolas Frances, Sylvia Herter, Regula B. Buser, Jitka Somandin, Sarah Diggelmann, Florian Limani, Thorsten Lehr, Marina Bacac, Antje-Christine Walz
    Molecular Cancer Therapeutics Feb 2021, 20 (2) 357-366; DOI: 10.1158/1535-7163.MCT-20-0269
  • Development of Novel Antibody–Camptothecin Conjugates
    Ryan D. Lyski, Lauren B. Bou, Uland Y. Lau, David W. Meyer, Julia H. Cochran, Nicole M. Okeley, Kim K. Emmerton, Francisco Zapata, Jessica K. Simmons, Esther S. Trueblood, David J. Ortiz, Margo C. Zaval, Katie M. Snead, Steven Jin, Lauren M. Farr, Maureen C. Ryan, Peter D. Senter, Scott C. Jeffrey
    Molecular Cancer Therapeutics Feb 2021, 20 (2) 329-339; DOI: 10.1158/1535-7163.MCT-20-0526

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Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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