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LILRB4-targeting Antibody–Drug Conjugates for the Treatment of Acute Myeloid Leukemia
Yasuaki Anami, Mi Deng, Xun Gui, Aiko Yamaguchi, Chisato M. Yamazaki, Ningyan Zhang, Cheng Cheng Zhang, Zhiqiang An, Kyoji Tsuchikama

Molecular Cancer Therapeutics Sep 2020, DOI: 10.1158/1535-7163.MCT-20-0407
Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody
Amir A. Al-Khami, Sawsan Youssef, Yasmina Abdiche, HoangKim Nguyen, Joyce Chou, Christopher R. Kimberlin, Sherman M. Chin, Cris Kamperschroer, Bart Jessen, Brent Kern, Natalija Budimir, Christopher P. Dillon, Allison Xu, Jerry D. Clark, Jeffrey Chou, Eugenia Kraynov, Arvind Rajpal, John C. Lin, Shahram Salek-Ardakani

Molecular Cancer Therapeutics Oct 2020, 19 (10) 2105-2116; DOI: 10.1158/1535-7163.MCT-20-0093
PF-06804103, A Site-specific Anti-HER2 Antibody–Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers
Edmund I. Graziani, Matthew Sung, Dangshe Ma, Bitha Narayanan, Kimberly Marquette, Sujiet Puthenveetil, L. Nathan Tumey, Jack Bikker, Jeffrey Casavant, Eric M. Bennett, Manoj B. Charati, Jonathon Golas, Christine Hosselet, Cynthia M. Rohde, George Hu, Magali Guffroy, Hadi Falahatpisheh, Martin Finkelstein, Tracey Clark, Frank Barletta, Lioudmila Tchistiakova, Judy Lucas, Edward Rosfjord, Frank Loganzo, Christopher J. O'Donnell, Hans-Peter Gerber, Puja Sapra

Molecular Cancer Therapeutics Oct 2020, 19 (10) 2068-2078; DOI: 10.1158/1535-7163.MCT-20-0237
Amivantamab (JNJ-61186372), an Fc Enhanced EGFR/cMet Bispecific Antibody, Induces Receptor Downmodulation and Antitumor Activity by Monocyte/Macrophage Trogocytosis
Smruthi Vijayaraghavan, Lorraine Lipfert, Kristen Chevalier, Barbara S. Bushey, Benjamin Henley, Ryan Lenhart, Jocelyn Sendecki, Marilda Beqiri, Hillary J. Millar, Kathryn Packman, Matthew V. Lorenzi, Sylvie Laquerre, Sheri L. Moores

Molecular Cancer Therapeutics Oct 2020, 19 (10) 2044-2056; DOI: 10.1158/1535-7163.MCT-20-0071
Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism
Marije B. Overdijk, Kristin Strumane, Frank J. Beurskens, Antonio Ortiz Buijsse, Claudine Vermot-Desroches, Boris S. Vuillermoz, Thessa Kroes, Bart de Jong, Naomi Hoevenaars, Richard G. Hibbert, Andreas Lingnau, Ulf Forssmann, Janine Schuurman, Paul W.H.I. Parren, Rob N. de Jong, Esther C.W. Breij

Molecular Cancer Therapeutics Oct 2020, 19 (10) 2126-2138; DOI: 10.1158/1535-7163.MCT-20-0044
Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies
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Molecular Cancer Therapeutics Oct 2020, 19 (10) 2089-2104; DOI: 10.1158/1535-7163.MCT-19-0003
Targeting Multiple EGFR-expressing Tumors with a Highly Potent Tumor-selective Antibody–Drug Conjugate
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Molecular Cancer Therapeutics Oct 2020, 19 (10) 2117-2125; DOI: 10.1158/1535-7163.MCT-20-0149
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody–Drug Conjugate in Patient-derived Xenografts
Adnan O. Abu-Yousif, Donna Cvet, Melissa Gallery, Bret M. Bannerman, Michelle L. Ganno, Michael D. Smith, Katharine C. Lai, Thomas A. Keating, Bradley Stringer, Afrand Kamali, Kurt Eng, Secil Koseoglu, Andy Zhu, Cindy Q. Xia, Melissa Saylor Landen, Maria Borland, Robbie Robertson, Jayaprakasam Bolleddula, Mark G. Qian, Jennifer Fretland, O. Petter Veiby

Molecular Cancer Therapeutics Oct 2020, 19 (10) 2079-2088; DOI: 10.1158/1535-7163.MCT-19-1102
Retargeted and Stealth-Modified Oncolytic Measles Viruses for Systemic Cancer Therapy in Measles Immune Patients
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Molecular Cancer Therapeutics Oct 2020, 19 (10) 2057-2067; DOI: 10.1158/1535-7163.MCT-20-0134
The Role of Specific ATP-Binding Cassette Transporters in the Acquired Resistance to Pyrrolobenzodiazepine Dimer–Containing Antibody–Drug Conjugates
Simon Corbett, Shiran Huang, Francesca Zammarchi, Philip W. Howard, Patrick H. van Berkel, John A. Hartley

Molecular Cancer Therapeutics Sep 2020, 19 (9) 1856-1865; DOI: 10.1158/1535-7163.MCT-20-0222

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