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More articles from Cancer Biology and Signal Transduction

Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI–Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation
Toshimitsu Yamaoka, Tohru Ohmori, Motoi Ohba, Satoru Arata, Yasunari Kishino, Yasunori Murata, Sojiro Kusumoto, Hiroo Ishida, Takao Shirai, Takashi Hirose, Tsukasa Ohnishi, Yasutsuna Sasaki

Molecular Cancer Therapeutics Dec 2016, 15 (12) 3040-3054; DOI: 10.1158/1535-7163.MCT-16-0313
Knockdown of Apolipoprotein E Enhanced Sensitivity of Hep3B Cells to Cardiac Steroids via Regulating Na⁺/K⁺-ATPase Signalosome
Miao Liu, Li-Xing Feng, Peng Sun, Wang Liu, Tian Mi, Min Lei, Wanying Wu, Baohong Jiang, Min Yang, Lihong Hu, De-An Guo, Xuan Liu

Molecular Cancer Therapeutics Dec 2016, 15 (12) 2955-2965; DOI: 10.1158/1535-7163.MCT-15-0961
Mutant BRAF Upregulates MCL-1 to Confer Apoptosis Resistance that Is Reversed by MCL-1 Antagonism and Cobimetinib in Colorectal Cancer
Hisato Kawakami, Shengbing Huang, Krishnendu Pal, Shamit K. Dutta, Debabrata Mukhopadhyay, Frank A. Sinicrope

Molecular Cancer Therapeutics Dec 2016, 15 (12) 3015-3027; DOI: 10.1158/1535-7163.MCT-16-0017
The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate–Lactate Exchange in BRAF-Mutant Human Melanoma Cells
Teresa Delgado-Goni, Maria Falck Miniotis, Slawomir Wantuch, Harold G. Parkes, Richard Marais, Paul Workman, Martin O. Leach, Mounia Beloueche-Babari

Molecular Cancer Therapeutics Dec 2016, 15 (12) 2987-2999; DOI: 10.1158/1535-7163.MCT-16-0068
Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma
Xiaoyun Dai, Kwang Seok Ahn, Ling Zhi Wang, Chulwon Kim, Amudha Deivasigamni, Frank Arfuso, Jae-Young Um, Alan Prem Kumar, Young-Chae Chang, Dhiraj Kumar, Gopal C. Kundu, Junji Magae, Boon Cher Goh, Kam Man Hui, Gautam Sethi

Molecular Cancer Therapeutics Dec 2016, 15 (12) 2966-2976; DOI: 10.1158/1535-7163.MCT-16-0391
Alkylating Agent–Induced NRF2 Blocks Endoplasmic Reticulum Stress–Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis
Alfeu Zanotto-Filho, V. Pragathi Masamsetti, Eva Loranc, Sonal S. Tonapi, Aparna Gorthi, Xavier Bernard, Rosângela Mayer Gonçalves, José C.F. Moreira, Yidong Chen, Alexander J.R. Bishop

Molecular Cancer Therapeutics Dec 2016, 15 (12) 3000-3014; DOI: 10.1158/1535-7163.MCT-16-0271
Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors
Timothy A. Marlowe, Felicia L. Lenzo, Sheila A. Figel, Abigail T. Grapes, William G. Cance

Molecular Cancer Therapeutics Dec 2016, 15 (12) 3028-3039; DOI: 10.1158/1535-7163.MCT-16-0366
Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models
Derek P. Logsdon, Michelle Grimard, Meihua Luo, Safi Shahda, Yanlin Jiang, Yan Tong, Zhangsheng Yu, Nicholas Zyromski, Ernestina Schipani, Fabrizio Carta, Claudiu T. Supuran, Murray Korc, Mircea Ivan, Mark R. Kelley, Melissa L. Fishel

Molecular Cancer Therapeutics Nov 2016, 15 (11) 2722-2732; DOI: 10.1158/1535-7163.MCT-16-0253
IQGAP1 Scaffold–MAP Kinase Interactions Enhance Multiple Myeloma Clonogenic Growth and Self-Renewal
Christian B. Gocke, Ross McMillan, Qiuju Wang, Asma Begum, Vesselin R. Penchev, Syed A. Ali, Ivan Borrello, Carol Ann Huff, William Matsui

Molecular Cancer Therapeutics Nov 2016, 15 (11) 2733-2739; DOI: 10.1158/1535-7163.MCT-16-0323
Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2
Alexey V. Danilov, Shanhu Hu, Bernardo Orr, Kristina Godek, Lisa Maria Mustachio, David Sekula, Xi Liu, Masanori Kawakami, Faye M. Johnson, Duane A. Compton, Sarah J. Freemantle, Ethan Dmitrovsky

Molecular Cancer Therapeutics Nov 2016, 15 (11) 2758-2766; DOI: 10.1158/1535-7163.MCT-16-0127

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