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More articles from Cancer Biology and Signal Transduction

ABCB1 Mediates Cabazitaxel–Docetaxel Cross-Resistance in Advanced Prostate Cancer
Alan P. Lombard, Chengfei Liu, Cameron M. Armstrong, Vito Cucchiara, Xinwei Gu, Wei Lou, Christopher P. Evans, Allen C. Gao

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2257-2266; DOI: 10.1158/1535-7163.MCT-17-0179
JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non–Small Cell Lung Cancer
Kazuhiko Shien, Vassiliki A. Papadimitrakopoulou, Dennis Ruder, Carmen Behrens, Li Shen, Neda Kalhor, Juhee Song, J. Jack Lee, Jing Wang, Ximing Tang, Roy S. Herbst, Shinichi Toyooka, Luc Girard, John D. Minna, Jonathan M. Kurie, Ignacio I. Wistuba, Julie G. Izzo

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2234-2245; DOI: 10.1158/1535-7163.MCT-17-0148
The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy
Michael P. Sanderson, Marco H. Hofmann, Pilar Garin-Chesa, Norbert Schweifer, Andreas Wernitznig, Stefan Fischer, Astrid Jeschko, Reiner Meyer, Jürgen Moll, Thomas Pecina, Heribert Arnhof, Ulrike Weyer-Czernilofsky, Stephan K. Zahn, Günther R. Adolf, Norbert Kraut

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2223-2233; DOI: 10.1158/1535-7163.MCT-17-0336
Decitabine Priming Enhances Mucin 1 Inhibition Mediated Disruption of Redox Homeostasis in Cutaneous T-Cell Lymphoma
Salvia Jain, Abigail Washington, Rebecca Karp Leaf, Parul Bhargava, Rachael A. Clark, Thomas S. Kupper, Dina Stroopinsky, Athalia Pyzer, Leandra Cole, Myrna Nahas, Arie Apel, Jacalyn Rosenblatt, Jon Arnason, Donald Kufe, David Avigan

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2304-2314; DOI: 10.1158/1535-7163.MCT-17-0060
The Tumor-Suppressor Protein OPCML Potentiates Anti–EGFR- and Anti–HER2-Targeted Therapy in HER2-Positive Ovarian and Breast Cancer
Elisa Zanini, Louay S. Louis, Jane Antony, Evdoxia Karali, Imoh S. Okon, Arthur B. McKie, Sebastian Vaughan, Mona El-Bahrawy, Justin Stebbing, Chiara Recchi, Hani Gabra

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2246-2256; DOI: 10.1158/1535-7163.MCT-17-0081
Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor–Chromatin Interactions
Kush Dalal, Meixia Che, Nanette S. Que, Aishwariya Sharma, Rendong Yang, Nada Lallous, Hendrik Borgmann, Deniz Ozistanbullu, Ronnie Tse, Fuqiang Ban, Huifang Li, Kevin J. Tam, Mani Roshan-Moniri, Eric LeBlanc, Martin E. Gleave, Daniel T. Gewirth, Scott M. Dehm, Artem Cherkasov, Paul S. Rennie

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2281-2291; DOI: 10.1158/1535-7163.MCT-17-0259
Ormeloxifene Suppresses Prostate Tumor Growth and Metastatic Phenotypes via Inhibition of Oncogenic β-catenin Signaling and EMT Progression
Bilal Bin Hafeez, Aditya Ganju, Mohammed Sikander, Vivek K. Kashyap, Zubair Bin Hafeez, Neeraj Chauhan, Shabnam Malik, Andrew E. Massey, Manish K. Tripathi, Fathi T. Halaweish, Nadeem Zafar, Man M. Singh, Murali M. Yallapu, Subhash C. Chauhan, Meena Jaggi

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2267-2280; DOI: 10.1158/1535-7163.MCT-17-0157
Inactivation of the Kinase Domain of CDK10 Prevents Tumor Growth in a Preclinical Model of Colorectal Cancer, and Is Accompanied by Downregulation of Bcl-2
Louis-Bastien Weiswald, Mohammad R. Hasan, John C.T. Wong, Clarissa C. Pasiliao, Mahbuba Rahman, Jianhua Ren, Yaling Yin, Samuel Gusscott, Sophie Vacher, Andrew P. Weng, Hagen F. Kennecke, Ivan Bièche, David F. Schaeffer, Donald T. Yapp, Isabella T. Tai

Molecular Cancer Therapeutics Oct 2017, 16 (10) 2292-2303; DOI: 10.1158/1535-7163.MCT-16-0666
Inhibition of Aurora A and Aurora B Is Required for the Sensitivity of HPV-Driven Cervical Cancers to Aurora Kinase Inhibitors
David Martin, Sora Fallaha, Martina Proctor, Alexander Stevenson, Lewis Perrin, Nigel McMillan, Brian Gabrielli

Molecular Cancer Therapeutics Sep 2017, 16 (9) 1934-1941; DOI: 10.1158/1535-7163.MCT-17-0159
Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor
Shan Zeng, Adrian M. Seifert, Jennifer Q. Zhang, Michael J. Cavnar, Teresa S. Kim, Vinod P. Balachandran, Juan A. Santamaria-Barria, Noah A. Cohen, Michael J. Beckman, Benjamin D. Medina, Ferdinand Rossi, Megan H. Crawley, Jennifer K. Loo, Joanna H. Maltbaek, Peter Besmer, Cristina R. Antonescu, Ronald P. DeMatteo

Molecular Cancer Therapeutics Sep 2017, 16 (9) 1954-1966; DOI: 10.1158/1535-7163.MCT-17-0139

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