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Molecular Cancer Therapeutics
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Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

Fabienne Baffert, Catherine H. Régnier, Alain De Pover, Carole Pissot-Soldermann, Gisele A. Tavares, Francesca Blasco, Josef Brueggen, Patrick Chène, Peter Drueckes, Dirk Erdmann, Pascal Furet, Marc Gerspacher, Marc Lang, David Ledieu, Lynda Nolan, Stephan Ruetz, Joerg Trappe, Eric Vangrevelinghe, Markus Wartmann, Lorenza Wyder, Francesco Hofmann and Thomas Radimerski
Fabienne Baffert
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Catherine H. Régnier
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Alain De Pover
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Carole Pissot-Soldermann
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Gisele A. Tavares
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Josef Brueggen
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Patrick Chène
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Lorenza Wyder
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Francesco Hofmann
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DOI: 10.1158/1535-7163.MCT-10-0053 Published July 2010
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Article Information

Volume 9, Issue 7, pp. 1945-1955

DOI 
https://doi.org/10.1158/1535-7163.MCT-10-0053
PubMed 
20587663

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received January 20, 2010
  • Revision received April 16, 2010
  • Accepted May 10, 2010
  • Published first June 29, 2010.

Article Versions

  • Previous version (June 29, 2010 - 08:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2010 American Association for Cancer Research.

Author Information

  1. Fabienne Baffert1,
  2. Catherine H. Régnier1,
  3. Alain De Pover1,
  4. Carole Pissot-Soldermann2,
  5. Gisele A. Tavares3,
  6. Francesca Blasco4,
  7. Josef Brueggen1,
  8. Patrick Chène1,
  9. Peter Drueckes3,
  10. Dirk Erdmann1,
  11. Pascal Furet2,
  12. Marc Gerspacher2,
  13. Marc Lang2,
  14. David Ledieu5,
  15. Lynda Nolan5,
  16. Stephan Ruetz1,
  17. Joerg Trappe3,
  18. Eric Vangrevelinghe2,
  19. Markus Wartmann1,
  20. Lorenza Wyder1,
  21. Francesco Hofmann1 and
  22. Thomas Radimerski1
  1. Authors' Affiliations: 1Disease Area Oncology, 2Global Discovery Chemistry, 3Center for Proteomic Chemistry, 4Metabolism and Pharmacokinetics, and 5Preclinical Safety Clinical Pathology, Novartis Institutes for BioMedical Research, Basel, Switzerland
  1. Corresponding Authors:
    F. Hofmann and T. Radimerski, Disease Area Oncology, Novartis Institutes for BioMedical Research, Klybeckstrasse 141, 4057 Basel, Switzerland. Phone: 41-61-696-2064; Fax: 41-61-696-3835. E-mail: francesco.hofmann{at}novartis.com and thomas.radimerski{at}novartis.com
  • Current address for L. Wyder: Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland.

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Molecular Cancer Therapeutics: 9 (7)
July 2010
Volume 9, Issue 7
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Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805
Fabienne Baffert, Catherine H. Régnier, Alain De Pover, Carole Pissot-Soldermann, Gisele A. Tavares, Francesca Blasco, Josef Brueggen, Patrick Chène, Peter Drueckes, Dirk Erdmann, Pascal Furet, Marc Gerspacher, Marc Lang, David Ledieu, Lynda Nolan, Stephan Ruetz, Joerg Trappe, Eric Vangrevelinghe, Markus Wartmann, Lorenza Wyder, Francesco Hofmann and Thomas Radimerski
Mol Cancer Ther July 1 2010 (9) (7) 1945-1955; DOI: 10.1158/1535-7163.MCT-10-0053

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Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805
Fabienne Baffert, Catherine H. Régnier, Alain De Pover, Carole Pissot-Soldermann, Gisele A. Tavares, Francesca Blasco, Josef Brueggen, Patrick Chène, Peter Drueckes, Dirk Erdmann, Pascal Furet, Marc Gerspacher, Marc Lang, David Ledieu, Lynda Nolan, Stephan Ruetz, Joerg Trappe, Eric Vangrevelinghe, Markus Wartmann, Lorenza Wyder, Francesco Hofmann and Thomas Radimerski
Mol Cancer Ther July 1 2010 (9) (7) 1945-1955; DOI: 10.1158/1535-7163.MCT-10-0053
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Molecular Cancer Therapeutics
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