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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Evaluation of Selective γ-Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial Design

Ping Wei, Marlena Walls, Ming Qiu, Richard Ding, Robert H. Denlinger, Anthony Wong, Kosta Tsaparikos, Jitesh P. Jani, Natilie Hosea, Michelle Sands, Sophia Randolph and Tod Smeal
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Jitesh P. Jani
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DOI: 10.1158/1535-7163.MCT-10-0034 Published June 2010
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Total437645653102

Cited By

Article Information

Volume 9, Issue 6, pp. 1618-1628

DOI 
https://doi.org/10.1158/1535-7163.MCT-10-0034
PubMed 
20530712

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received January 13, 2010
  • Accepted March 12, 2010
  • Published first June 8, 2010.

Article Versions

  • Previous version (June 8, 2010 - 10:02).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2010 American Association for Cancer Research.

Author Information

  1. Ping Wei1,
  2. Marlena Walls1,
  3. Ming Qiu1,
  4. Richard Ding1,
  5. Robert H. Denlinger2,
  6. Anthony Wong2,
  7. Kosta Tsaparikos1,
  8. Jitesh P. Jani1,
  9. Natilie Hosea3,
  10. Michelle Sands3,
  11. Sophia Randolph4 and
  12. Tod Smeal1
  1. Authors' Affiliations: 1Drug Discovery Group and Oncology Research Unit, 2Drug Safety Research and Development, 3Pharmacokinetics, Dynamics and Metabolism, and 4Translational Medicine Group and Oncology Business Unit, Pfizer Global Research and Development, La Jolla Laboratories, San Diego, California
  1. Corresponding Author:
    Tod Smeal, Oncology Research Unit, Pfizer Global Research and Development, La Jolla Laboratories, 10724 Science Center Drive, La Jolla, CA 92121. Phone: 858-622-8081; Fax: 858-526-4121. E-mail: tod.smeal{at}pfizer.com
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Molecular Cancer Therapeutics: 9 (6)
June 2010
Volume 9, Issue 6
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Evaluation of Selective γ-Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial Design
Ping Wei, Marlena Walls, Ming Qiu, Richard Ding, Robert H. Denlinger, Anthony Wong, Kosta Tsaparikos, Jitesh P. Jani, Natilie Hosea, Michelle Sands, Sophia Randolph and Tod Smeal
Mol Cancer Ther June 1 2010 (9) (6) 1618-1628; DOI: 10.1158/1535-7163.MCT-10-0034

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Evaluation of Selective γ-Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial Design
Ping Wei, Marlena Walls, Ming Qiu, Richard Ding, Robert H. Denlinger, Anthony Wong, Kosta Tsaparikos, Jitesh P. Jani, Natilie Hosea, Michelle Sands, Sophia Randolph and Tod Smeal
Mol Cancer Ther June 1 2010 (9) (6) 1618-1628; DOI: 10.1158/1535-7163.MCT-10-0034
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Molecular Cancer Therapeutics
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