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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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About the Cover

Cover image

Cover image expansion

Immunofluorescent image of untreated A549 lung adenocarcinoma cells. A549 cells seeded on collagen coated coverslips were stained for focal adhesions (antivinculin antibody; green) and F-Actin stress fibers (rhodamine conjugated phalloidin; red). Nuclei were visualized by DAPI staining (blue). It was found that Nutlin 3, a small molecule inhibitor of MDM2, decreases F-actin stress fibers, focal adhesions and invasion in p53wt human cancer cells. For details, see article by Moran and Maki on page 895.

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Molecular Cancer Therapeutics: 9 (4)
April 2010
Volume 9, Issue 4
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Issue Highlights

  • Nutlin-3a Induces Cytoskeletal Rearrangement and Inhibits the Migration and Invasion Capacity of p53 Wild-Type Cancer Cells
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Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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