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Molecular Cancer Therapeutics
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Therapeutic Discovery

Modulation of 4E-BP1 Function as a Critical Determinant of Enzastaurin-Induced Apoptosis

Chad A. Dumstorf, Bruce W. Konicek, Ann M. McNulty, Stephen H. Parsons, Luc Furic, Nahum Sonenberg and Jeremy R. Graff
Chad A. Dumstorf
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Bruce W. Konicek
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Ann M. McNulty
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Stephen H. Parsons
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Luc Furic
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Nahum Sonenberg
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Jeremy R. Graff
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DOI: 10.1158/1535-7163.MCT-10-0413 Published December 2010
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Article Information

Volume 9, Issue 12, pp. 3158-3163

DOI 
https://doi.org/10.1158/1535-7163.MCT-10-0413
PubMed 
20971826

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received May 5, 2010
  • Revision received October 12, 2010
  • Accepted October 12, 2010
  • Published first October 22, 2010.

Article Versions

  • Previous version (October 22, 2010 - 07:19).
  • You are viewing the most recent version of this article.
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©2010 American Association for Cancer Research.

Author Information

  1. Chad A. Dumstorf1,
  2. Bruce W. Konicek1,
  3. Ann M. McNulty1,
  4. Stephen H. Parsons1,
  5. Luc Furic2,
  6. Nahum Sonenberg2 and
  7. Jeremy R. Graff1
  1. Authors' Affiliations: 1Lilly Research Labs, Eli Lilly and Company, Indianapolis, Indiana; and 2Department of Biochemistry and Goodman Cancer Center, McGill University, Montreal, Quebec, Canada
  1. Corresponding Author:
    Jeremy R. Graff, Cancer Biology and Patient Tailoring, Lilly Research Labs, Lilly Corporate Center, DC 0546, Indianapolis, IN 46285. Phone: 317-277-0220; Fax: 1-317-277-3652. E-mail: graff_jeremy{at}lilly.com
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Molecular Cancer Therapeutics: 9 (12)
December 2010
Volume 9, Issue 12
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Modulation of 4E-BP1 Function as a Critical Determinant of Enzastaurin-Induced Apoptosis
Chad A. Dumstorf, Bruce W. Konicek, Ann M. McNulty, Stephen H. Parsons, Luc Furic, Nahum Sonenberg and Jeremy R. Graff
Mol Cancer Ther December 1 2010 (9) (12) 3158-3163; DOI: 10.1158/1535-7163.MCT-10-0413

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Modulation of 4E-BP1 Function as a Critical Determinant of Enzastaurin-Induced Apoptosis
Chad A. Dumstorf, Bruce W. Konicek, Ann M. McNulty, Stephen H. Parsons, Luc Furic, Nahum Sonenberg and Jeremy R. Graff
Mol Cancer Ther December 1 2010 (9) (12) 3158-3163; DOI: 10.1158/1535-7163.MCT-10-0413
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Molecular Cancer Therapeutics
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