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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines

Zhenfeng Duan, Edwin Choy, David Harmon, Cao Yang, Keinosuke Ryu, Joseph Schwab, Henry Mankin and Francis J. Hornicek
Zhenfeng Duan
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Edwin Choy
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David Harmon
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Cao Yang
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Keinosuke Ryu
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Joseph Schwab
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Henry Mankin
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Francis J. Hornicek
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DOI: 10.1158/1535-7163.MCT-09-0115 Published August 2009
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Article Information

Volume 8, Issue 8, pp. 2122-2130

DOI 
https://doi.org/10.1158/1535-7163.MCT-09-0115
PubMed 
19638450

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received February 9, 2009
  • Revision received April 9, 2009
  • Accepted April 29, 2009
  • Published first July 28, 2009.

Article Versions

  • Previous version (July 28, 2009 - 09:08).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2009 American Association for Cancer Research.

Author Information

  1. Zhenfeng Duan1,
  2. Edwin Choy2,3,
  3. David Harmon2,3,
  4. Cao Yang1,
  5. Keinosuke Ryu1,
  6. Joseph Schwab1,
  7. Henry Mankin1 and
  8. Francis J. Hornicek1
  1. 1Center for Sarcoma and Connective Tissue Oncology, 2MGH Cancer Center, and 3Department of Hematology-Oncology, Massachusetts General Hospital, Boston, Massachusetts
  1. Requests for reprints:
    Zhenfeng Duan, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Jackson Building, Room 1115, 55 Fruit Street, Boston, MA 02114. Phone: 617-724-3144; Fax: 617-724-7396. E-mail: zduan{at}partners.org
  1. Z. Duan and E. Choy contributed equally to this work.

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Molecular Cancer Therapeutics: 8 (8)
August 2009
Volume 8, Issue 8
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Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines
Zhenfeng Duan, Edwin Choy, David Harmon, Cao Yang, Keinosuke Ryu, Joseph Schwab, Henry Mankin and Francis J. Hornicek
Mol Cancer Ther August 1 2009 (8) (8) 2122-2130; DOI: 10.1158/1535-7163.MCT-09-0115

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Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines
Zhenfeng Duan, Edwin Choy, David Harmon, Cao Yang, Keinosuke Ryu, Joseph Schwab, Henry Mankin and Francis J. Hornicek
Mol Cancer Ther August 1 2009 (8) (8) 2122-2130; DOI: 10.1158/1535-7163.MCT-09-0115
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Molecular Cancer Therapeutics
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