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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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About the Cover

Cover image

Cover image expansion

Genistein promotes the re-organization of PODs to a dot-like pattern. The diffused microspeckled-like distribution of PML observed in APL cell line NB4 cells (DMSO-upper panels) was converted to a more centralized dot-like distribution after genistein treatment (genistein-upper panels). The effect of genistein on re-organization of PODs was very similar to that of RA (Retinoic acid panels). Similarly, the diffused nucleo-cytoplasmic distribution of N-CoR (DMSO-lower panels) was changed to a predominantly nuclear distribution pattern and exhibited significant co-localization with PML after genistein treatment (genistein-lower panels). For details, see Ng et al. in this issue.

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Molecular Cancer Therapeutics: 6 (8)
August 2007
Volume 6, Issue 8
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Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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