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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Table of Contents

Reviews

  • Reviews
    Lessons learned in the development of targeted therapy for malignant gliomas
    Antonio M.P. Omuro, Sandrine Faivre and Eric Raymond
    Mol Cancer Ther July 1 2007 6 (7) 1909-1919; DOI:10.1158/1535-7163.MCT-07-0047

  • Reviews
    Regulation of mitosis via mitotic kinases: new opportunities for cancer management
    Travis L. Schmit and Nihal Ahmad
    Mol Cancer Ther July 1 2007 6 (7) 1920-1931; DOI:10.1158/1535-7163.MCT-06-0781

Research Articles

  • Research Articles
    Platelet-derived growth factor receptor-α: a novel therapeutic target in human hepatocellular cancer
    Peggy Stock, Dulabh Monga, Xinping Tan, Amanda Micsenyi, Nick Loizos and Satdarshan P.S. Monga
    Mol Cancer Ther July 1 2007 6 (7) 1932-1941; DOI:10.1158/1535-7163.MCT-06-0720

  • Research Articles
    Intratumoral expression of respiratory syncytial virus fusion protein in combination with cytokines encoded by adenoviral vectors as in situ tumor vaccine for colorectal cancer
    Dennis Hoffmann, Wibke Bayer, Thomas Grunwald and Oliver Wildner
    Mol Cancer Ther July 1 2007 6 (7) 1942-1950; DOI:10.1158/1535-7163.MCT-06-0790

  • Research Articles
    Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cells
    Ellen Weisberg, Andrew L. Kung, Renee D. Wright, Daisy Moreno, Laurie Catley, Arghya Ray, Leigh Zawel, Mary Tran, Jan Cools, Gary Gilliland, Constantine Mitsiades, Douglas W. McMillin, Jingrui Jiang, Elizabeth Hall-Meyers and James D. Griffin
    Mol Cancer Ther July 1 2007 6 (7) 1951-1961; DOI:10.1158/1535-7163.MCT-06-0810

  • Research Articles
    Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion
    Anne S. Tsao, Dandan He, Babita Saigal, Suyu Liu, J. Jack Lee, Srinivasa Bakkannagari, Nelson G. Ordonez, Waun Ki Hong, Ignacio Wistuba and Faye M. Johnson
    Mol Cancer Ther July 1 2007 6 (7) 1962-1972; DOI:10.1158/1535-7163.MCT-07-0052

  • Research Articles
    Nuclear factor-κB activation: a molecular therapeutic target for estrogen receptor–negative and epidermal growth factor receptor family receptor–positive human breast cancer
    Sindhu Singh, Qian Shi, Shannon T. Bailey, Marek J. Palczewski, Arthur B. Pardee, J. Dirk Iglehart and Debajit K. Biswas
    Mol Cancer Ther July 1 2007 6 (7) 1973-1982; DOI:10.1158/1535-7163.MCT-07-0063

  • Research Articles
    Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-κB signaling
    Christine L. Curry, Laura L. Reed, Eugenia Broude, Todd E. Golde, Lucio Miele and Kimberly E. Foreman
    Mol Cancer Ther July 1 2007 6 (7) 1983-1992; DOI:10.1158/1535-7163.MCT-07-0093

  • Research Articles
    Ovarian cancer cell–derived migration inhibitory factor enhances tumor growth, progression, and angiogenesis
    Thorsten Hagemann, Stephen C. Robinson, Richard G. Thompson, Kellie Charles, Hagen Kulbe and Frances R. Balkwill
    Mol Cancer Ther July 1 2007 6 (7) 1993-2002; DOI:10.1158/1535-7163.MCT-07-0118

  • Research Articles
    ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo
    Laura Rosanò, Valeriana Di Castro, Francesca Spinella, Maria Rita Nicotra, Pier Giorgio Natali and Anna Bagnato
    Mol Cancer Ther July 1 2007 6 (7) 2003-2011; DOI:10.1158/1535-7163.MCT-07-0151

  • Research Articles
    Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity
    Rakesh Kumar, Victoria B. Knick, Sharon K. Rudolph, Jennifer H. Johnson, Renae M. Crosby, Ming-Chih Crouthamel, Teresa M. Hopper, Charles G. Miller, Laura E. Harrington, James A. Onori, Robert J. Mullin, Tona M. Gilmer, Anne T. Truesdale, Andrea H. Epperly, Amogh Boloor, Jeffrey A. Stafford, Deirdre K. Luttrell and Mui Cheung
    Mol Cancer Ther July 1 2007 6 (7) 2012-2021; DOI:10.1158/1535-7163.MCT-07-0193

  • Research Articles
    Preventive effects of Polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols
    Ronald A. Lubet, Chung S. Yang, Mao-Jung Lee, Yukihiko Hara, Izet M. Kapetanovic, James A. Crowell, Vernon E. Steele, M. Margaret Juliana and Clinton J. Grubbs
    Mol Cancer Ther July 1 2007 6 (7) 2022-2028; DOI:10.1158/1535-7163.MCT-07-0058

  • Research Articles
    The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway
    Heath A. Elrod, Yi-Dan Lin, Ping Yue, Xuerong Wang, Sagar Lonial, Fadlo R. Khuri and Shi-Yong Sun
    Mol Cancer Ther July 1 2007 6 (7) 2029-2038; DOI:10.1158/1535-7163.MCT-07-0004

  • Research Articles
    TNF-α–based accentuation in cryoinjury—dose, delivery, and response
    Raghav Goel, David Swanlund, James Coad, Guilio F. Paciotti and John C. Bischof
    Mol Cancer Ther July 1 2007 6 (7) 2039-2047; DOI:10.1158/1535-7163.MCT-06-0676

  • Research Articles
    Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1α,25-dihydroxyvitamin D3 in prostate cancer cells
    Yong Xu, Fang Fang, Daret K. St. Clair, Sajni Josson, Pradoldej Sompol, Ivan Spasojevic and William H. St. Clair
    Mol Cancer Ther July 1 2007 6 (7) 2048-2056; DOI:10.1158/1535-7163.MCT-06-0700

  • Research Articles
    A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells
    Shan Lu, Amy Wang, Shan Lu and Zhongyun Dong
    Mol Cancer Ther July 1 2007 6 (7) 2057-2064; DOI:10.1158/1535-7163.MCT-06-0735

  • Research Articles
    Trastuzumab causes antibody-dependent cellular cytotoxicity–mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance
    Márk Barok, Jorma Isola, Zsuzsanna Pályi-Krekk, Péter Nagy, István Juhász, György Vereb, Päivikki Kauraniemi, Anita Kapanen, Minna Tanner, György Vereb and János Szöllösi
    Mol Cancer Ther July 1 2007 6 (7) 2065-2072; DOI:10.1158/1535-7163.MCT-06-0766

  • Research Articles
    2-Methoxy antimycin reveals a unique mechanism for Bcl-xL inhibition
    Pamela S. Schwartz, Michael K. Manion, Christine B. Emerson, John S. Fry, Craig M. Schulz, Ian R. Sweet and David M. Hockenbery
    Mol Cancer Ther July 1 2007 6 (7) 2073-2080; DOI:10.1158/1535-7163.MCT-06-0767

  • Research Articles
    The HLA A*0201–restricted hTERT540–548 peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor
    Marco A. Purbhoo, Yi Li, Deborah H. Sutton, Joanna E. Brewer, Emma Gostick, Giovanna Bossi, Bruno Laugel, Ruth Moysey, Emma Baston, Nathaniel Liddy, Brian Cameron, Alan D. Bennett, Rebecca Ashfield, Anita Milicic, David A. Price, Brendan J. Classon, Andrew K. Sewell and Bent K. Jakobsen
    Mol Cancer Ther July 1 2007 6 (7) 2081-2091; DOI:10.1158/1535-7163.MCT-07-0092

  • Research Articles
    Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein
    Kazuhiro Katayama, Sho Yoshioka, Satomi Tsukahara, Junko Mitsuhashi and Yoshikazu Sugimoto
    Mol Cancer Ther July 1 2007 6 (7) 2092-2102; DOI:10.1158/1535-7163.MCT-07-0148

  • Research Articles
    TRAIL therapy in non–small cell lung cancer cells: sensitization to death receptor–mediated apoptosis by proteasome inhibitor bortezomib
    Jens Voortman, Tatiana P. Resende, Mohamed A.I. Abou El Hassan, Giuseppe Giaccone and Frank A.E. Kruyt
    Mol Cancer Ther July 1 2007 6 (7) 2103-2112; DOI:10.1158/1535-7163.MCT-07-0167

  • Research Articles
    Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities
    Karen Liby, Tadashi Honda, Charlotte R. Williams, Renee Risingsong, Darlene B. Royce, Nanjoo Suh, Albena T. Dinkova-Kostova, Katherine K. Stephenson, Paul Talalay, Chitra Sundararajan, Gordon W. Gribble and Michael B. Sporn
    Mol Cancer Ther July 1 2007 6 (7) 2113-2119; DOI:10.1158/1535-7163.MCT-07-0180

  • Research Articles
    Novel antagonists of the thioesterase domain of human fatty acid synthase
    Robyn D. Richardson and Jeffrey W. Smith
    Mol Cancer Ther July 1 2007 6 (7) 2120-2126; DOI:10.1158/1535-7163.MCT-07-0187

  • Research Articles
    Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21WAF1/CIP1 expression with rapamycin
    Chun-Te Chiang, Tzong-Der Way and Jen-Kun Lin
    Mol Cancer Ther July 1 2007 6 (7) 2127-2138; DOI:10.1158/1535-7163.MCT-07-0107

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Molecular Cancer Therapeutics: 6 (7)
July 2007
Volume 6, Issue 7
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  • Lessons learned in the development of targeted therapy for malignant gliomas

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Molecular Cancer Therapeutics
eISSN: 1538-8514
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