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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Table of Contents

Obituary

  • Obituary
    Christoper J. Michejda
    Jan M. Woynarowski
    Mol Cancer Ther May 1 2007 6 (5) 1475-1476; DOI:10.1158/1535-7163.MCT-07-0270

Spotlight on Clinical Response

  • Spotlight on Clinical Response
    Studies in target-based treatment
    Razelle Kurzrock
    Mol Cancer Ther May 1 2007 6 (5) 1477-1477; DOI:10.1158/1535-7163.MCT-07-0255

  • Spotlight on Clinical Response
    p53 therapy in a patient with Li-Fraumeni syndrome
    Neil Senzer, John Nemunaitis, Michael Nemunaitis, Jeffrey Lamont, Martin Gore, Hani Gabra, Rosalind Eeles, Nayanta Sodha, Frank J. Lynch, Louis A. Zumstein, Kerstin B. Menander, Robert E. Sobol and Sunil Chada
    Mol Cancer Ther May 1 2007 6 (5) 1478-1482; DOI:10.1158/1535-7163.MCT-07-0125

Spotlight on Molecular Profiling

  • Spotlight on Molecular Profiling
    MicroRNA expression profiles for the NCI-60 cancer cell panel
    Paul E. Blower, Joseph S. Verducci, Shili Lin, Jin Zhou, Ji-Hyun Chung, Zunyan Dai, Chang-Gong Liu, William Reinhold, Philip L. Lorenzi, Eric P. Kaldjian, Carlo M. Croce, John N. Weinstein and Wolfgang Sadee
    Mol Cancer Ther May 1 2007 6 (5) 1483-1491; DOI:10.1158/1535-7163.MCT-07-0009

Research Articles: Therapeutics, Targets, and Development

  • Research Articles: Therapeutics, Targets, and Development
    Defining regional infusion treatment strategies for extremity melanoma: comparative analysis of melphalan and temozolomide as regional chemotherapeutic agents
    Yasunori Yoshimoto, Christina K. Augustine, Jin S. Yoo, Patricia A. Zipfel, M. Angelica Selim, Scott K. Pruitt, Henry S. Friedman, Francis Ali-Osman and Douglas S. Tyler
    Mol Cancer Ther May 1 2007 6 (5) 1492-1500; DOI:10.1158/1535-7163.MCT-06-0718

  • Research Articles: Therapeutics, Targets, and Development
    Inhibition of topoisomerase IIα and G2 cell cycle arrest by NK314, a novel benzo[c]phenanthridine currently in clinical trials
    Lei Guo, Xiaojun Liu, Kiyohiro Nishikawa and William Plunkett
    Mol Cancer Ther May 1 2007 6 (5) 1501-1508; DOI:10.1158/1535-7163.MCT-06-0780

  • Research Articles: Therapeutics, Targets, and Development
    Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer
    Antonio Jimeno, Gurulingappa Hallur, Audrey Chan, Xiangfeng Zhang, George Cusatis, Fonda Chan, Preeti Shah, Rongbing Chen, Ernest Hamel, Elizabeth Garrett-Mayer, Saeed Khan and Manuel Hidalgo
    Mol Cancer Ther May 1 2007 6 (5) 1509-1516; DOI:10.1158/1535-7163.MCT-06-0592

  • Research Articles: Therapeutics, Targets, and Development
    Fasudil inhibits vascular endothelial growth factor–induced angiogenesis in vitro and in vivo
    Limei Yin, Ken-ichirou Morishige, Toshifumi Takahashi, Kae Hashimoto, Seiji Ogata, Seiji Tsutsumi, Keiko Takata, Tsuyoshi Ohta, Jun Kawagoe, Kazuhiro Takahashi and Hirohisa Kurachi
    Mol Cancer Ther May 1 2007 6 (5) 1517-1525; DOI:10.1158/1535-7163.MCT-06-0689

  • Research Articles: Therapeutics, Targets, and Development
    Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor α
    Wilbert Zwart, Alexander Griekspoor, Mariska Rondaij, Desiree Verwoerd, Jacques Neefjes and Rob Michalides
    Mol Cancer Ther May 1 2007 6 (5) 1526-1533; DOI:10.1158/1535-7163.MCT-06-0750

  • Research Articles: Therapeutics, Targets, and Development
    Increased expression of cyclin B1 sensitizes prostate cancer cells to apoptosis induced by chemotherapy
    Lourdes A. Gomez, Alicia de las Pozas, Teresita Reiner, Kerry Burnstein and Carlos Perez-Stable
    Mol Cancer Ther May 1 2007 6 (5) 1534-1543; DOI:10.1158/1535-7163.MCT-06-0727

  • Research Articles: Therapeutics, Targets, and Development
    Cellular FLICE-inhibitory protein regulates chemotherapy-induced apoptosis in breast cancer cells
    Katherine M.A. Rogers, Michelle Thomas, Leeona Galligan, Timothy R. Wilson, Wendy L. Allen, Hidekazu Sakai, Patrick G. Johnston and Daniel B. Longley
    Mol Cancer Ther May 1 2007 6 (5) 1544-1551; DOI:10.1158/1535-7163.MCT-06-0673

  • Research Articles: Therapeutics, Targets, and Development
    Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53
    Harm C.A. Graat, Jan E. Carette, Frederik H.E. Schagen, Lyubomir T. Vassilev, Winald R. Gerritsen, Gertjan J.L. Kaspers, Paul I.J.M. Wuisman and Victor W. van Beusechem
    Mol Cancer Ther May 1 2007 6 (5) 1552-1561; DOI:10.1158/1535-7163.MCT-06-0631

  • Research Articles: Therapeutics, Targets, and Development
    5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNFα-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling
    Rong-Ying Su, Yee Chao, Tsai-Yu Chen, Duen-Yi Huang and Wan-Wan Lin
    Mol Cancer Ther May 1 2007 6 (5) 1562-1571; DOI:10.1158/1535-7163.MCT-06-0800

  • Research Articles: Therapeutics, Targets, and Development
    A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression
    Hui-Chiu Chang, Fang-Rong Chang, Yu-Chu Wang, Mei-Ren Pan, Wen-Chun Hung and Yang-Chang Wu
    Mol Cancer Ther May 1 2007 6 (5) 1572-1578; DOI:10.1158/1535-7163.MCT-06-0812

  • Research Articles: Therapeutics, Targets, and Development
    ZD1839 induces p15INK4b and causes G1 arrest by inhibiting the mitogen-activated protein kinase/extracellular signal–regulated kinase pathway
    Makoto Koyama, Youichirou Matsuzaki, Shingo Yogosawa, Toshiaki Hitomi, Mayumi Kawanaka and Toshiyuki Sakai
    Mol Cancer Ther May 1 2007 6 (5) 1579-1587; DOI:10.1158/1535-7163.MCT-06-0814

  • Research Articles: Therapeutics, Targets, and Development
    Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator–activated receptor γ agonists in colon cancer cells
    Sudhakar Chintharlapalli, Sabitha Papineni, Indira Jutooru, Alan McAlees and Stephen Safe
    Mol Cancer Ther May 1 2007 6 (5) 1588-1598; DOI:10.1158/1535-7163.MCT-07-0022

  • Research Articles: Therapeutics, Targets, and Development
    Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak
    Young-Ae Kim, Dong Xiao, Hui Xiao, Anna A. Powolny, Karen L. Lew, Megan L. Reilly, Yan Zeng, Zhou Wang and Shivendra V. Singh
    Mol Cancer Ther May 1 2007 6 (5) 1599-1609; DOI:10.1158/1535-7163.MCT-06-0754

  • Research Articles: Therapeutics, Targets, and Development
    Expression of human glutathione S-transferase P1 mediates the chemosensitivity of osteosarcoma cells
    Gangxiong Huang, Lisa Mills and Laura L. Worth
    Mol Cancer Ther May 1 2007 6 (5) 1610-1619; DOI:10.1158/1535-7163.MCT-06-0580

  • Research Articles: Therapeutics, Targets, and Development
    Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors
    Raushan T. Kurmasheva, Franklin C. Harwood and Peter J. Houghton
    Mol Cancer Ther May 1 2007 6 (5) 1620-1628; DOI:10.1158/1535-7163.MCT-06-0646

  • Research Articles: Therapeutics, Targets, and Development
    Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles
    Priti S. Hegde, David Rusnak, Melissa Bertiaux, Krystal Alligood, Jay Strum, Robert Gagnon and Tona M. Gilmer
    Mol Cancer Ther May 1 2007 6 (5) 1629-1640; DOI:10.1158/1535-7163.MCT-05-0399

  • Research Articles: Therapeutics, Targets, and Development
    Shikonin circumvents cancer drug resistance by induction of a necroptotic death
    Weidong Han, Ling Li, Shuang Qiu, Qinghua Lu, Qiangrong Pan, Ying Gu, Jianhong Luo and Xun Hu
    Mol Cancer Ther May 1 2007 6 (5) 1641-1649; DOI:10.1158/1535-7163.MCT-06-0511

  • Research Articles: Therapeutics, Targets, and Development
    Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation
    Jonathan A.F. Hannay, Juehui Liu, Quan-Sheng Zhu, Svetlana V. Bolshakov, Lan Li, Peter W.T. Pisters, Alexander J.F. Lazar, Dihua Yu, Raphael E. Pollock and Dina Lev
    Mol Cancer Ther May 1 2007 6 (5) 1650-1660; DOI:10.1158/1535-7163.MCT-06-0636

  • Research Articles: Therapeutics, Targets, and Development
    Transactivator of transcription–tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo
    Liyue Zhang, Edi Levi, Pralay Majumder, Yingjie Yu, Amro Aboukameel, Jianhua Du, Hu Xu, Ramzi Mohammad, James S. Hatfield, Anil Wali, Volkan Adsay, Adhip P.N. Majumdar and Arun K. Rishi
    Mol Cancer Ther May 1 2007 6 (5) 1661-1672; DOI:10.1158/1535-7163.MCT-06-0653

  • Research Articles: Therapeutics, Targets, and Development
    Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line
    Anna Herman-Antosiewicz, Hui Xiao, Karen L. Lew and Shivendra V. Singh
    Mol Cancer Ther May 1 2007 6 (5) 1673-1681; DOI:10.1158/1535-7163.MCT-06-0807

Correction

  • Correction
    Article on RAV12 antibody, oncosis, and antitumor activity
    Mol Cancer Ther May 1 2007 6 (5) 1682-1682; DOI:10.1158/1535-7163.MCT-06-5-COR

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Molecular Cancer Therapeutics: 6 (5)
May 2007
Volume 6, Issue 5
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Issue Highlights

  • Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles

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  • Obituary
  • Spotlight on Clinical Response
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Molecular Cancer Therapeutics
eISSN: 1538-8514
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