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Molecular Cancer Therapeutics
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Article

Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo

Holly K. Koblish, Shuyuan Zhao, Carol F. Franks, Robert R. Donatelli, Rose M. Tominovich, Louis V. LaFrance, Kristi A. Leonard, Joan M. Gushue, Daniel J. Parks, Raul R. Calvo, Karen L. Milkiewicz, Juan José Marugán, Pierre Raboisson, Maxwell D. Cummings, Bruce L. Grasberger, Dana L. Johnson, Tianbao Lu, Christopher J. Molloy and Anna C. Maroney
Holly K. Koblish
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Shuyuan Zhao
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Carol F. Franks
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Robert R. Donatelli
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Rose M. Tominovich
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Louis V. LaFrance
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Kristi A. Leonard
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Joan M. Gushue
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Daniel J. Parks
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Raul R. Calvo
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Karen L. Milkiewicz
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Juan José Marugán
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Pierre Raboisson
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Maxwell D. Cummings
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Bruce L. Grasberger
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Dana L. Johnson
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Tianbao Lu
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Christopher J. Molloy
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DOI: 10.1158/1535-7163.MCT-05-0199 Published January 2006
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Cited By

Article Information

Volume 5, Issue 1, pp. 160-169

DOI 
https://doi.org/10.1158/1535-7163.MCT-05-0199
PubMed 
16432175

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • November 2, 2005
  • June 17, 2005
  • September 21, 2005
  • Published first January 23, 2006.

Copyright & Usage 
American Association for Cancer Research

Author Information

  1. Holly K. Koblish,
  2. Shuyuan Zhao,
  3. Carol F. Franks,
  4. Robert R. Donatelli,
  5. Rose M. Tominovich,
  6. Louis V. LaFrance,
  7. Kristi A. Leonard,
  8. Joan M. Gushue,
  9. Daniel J. Parks,
  10. Raul R. Calvo,
  11. Karen L. Milkiewicz,
  12. Juan José Marugán,
  13. Pierre Raboisson,
  14. Maxwell D. Cummings,
  15. Bruce L. Grasberger,
  16. Dana L. Johnson,
  17. Tianbao Lu,
  18. Christopher J. Molloy and
  19. Anna C. Maroney
  1. Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Spring House, Pennsylvania
  1. Requests for reprints: Holly K. Koblish, Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Welsh and McKean Roads, Spring House, PA 19477. Phone: 215-628-5449; Fax: 215-628-5047. E-mail: hkoblis1{at}prdus.jnj.com
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Molecular Cancer Therapeutics: 5 (1)
January 2006
Volume 5, Issue 1
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Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo
Holly K. Koblish, Shuyuan Zhao, Carol F. Franks, Robert R. Donatelli, Rose M. Tominovich, Louis V. LaFrance, Kristi A. Leonard, Joan M. Gushue, Daniel J. Parks, Raul R. Calvo, Karen L. Milkiewicz, Juan José Marugán, Pierre Raboisson, Maxwell D. Cummings, Bruce L. Grasberger, Dana L. Johnson, Tianbao Lu, Christopher J. Molloy and Anna C. Maroney
Mol Cancer Ther January 1 2006 (5) (1) 160-169; DOI: 10.1158/1535-7163.MCT-05-0199

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Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo
Holly K. Koblish, Shuyuan Zhao, Carol F. Franks, Robert R. Donatelli, Rose M. Tominovich, Louis V. LaFrance, Kristi A. Leonard, Joan M. Gushue, Daniel J. Parks, Raul R. Calvo, Karen L. Milkiewicz, Juan José Marugán, Pierre Raboisson, Maxwell D. Cummings, Bruce L. Grasberger, Dana L. Johnson, Tianbao Lu, Christopher J. Molloy and Anna C. Maroney
Mol Cancer Ther January 1 2006 (5) (1) 160-169; DOI: 10.1158/1535-7163.MCT-05-0199
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Molecular Cancer Therapeutics
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