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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Table of Contents

Article

  • Article
    AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model
    I-Fen Chen, Fu Ou-Yang, Jen-Yu Hung, Jaw-Ching Liu, Hongying Wang, Shao-Chun Wang, Ming-Feng Hou, Gabriel N. Hortobagyi and Mien-Chie Hung
    Mol Cancer Ther January 1 2006 5 (1) 1-7; DOI:10.1158/1535-7163.MCT-05-0310

  • Article
    Epigenetic modification of SOCS-1 differentially regulates STAT3 activation in response to interleukin-6 receptor and epidermal growth factor receptor signaling through JAK and/or MEK in head and neck squamous cell carcinomas
    Tin Lap Lee, Jason Yeh, Carter Van Waes and Zhong Chen
    Mol Cancer Ther January 1 2006 5 (1) 8-19; DOI:10.1158/1535-7163.MCT-05-0069

  • Article
    Restoration of p53 function for selective Fas-mediated apoptosis in human and rat glioma cells in vitro and in vivo by a p53 COOH-terminal peptide
    Patrick B. Senatus, Yin Li, Christopher Mandigo, Gwen Nichols, Gaetan Moise, Yuehua Mao, Melandee D. Brown, Richard C. Anderson, Andrew T. Parsa, Paul W. Brandt-Rauf, Jeffrey N. Bruce and Robert L. Fine
    Mol Cancer Ther January 1 2006 5 (1) 20-28; DOI:10.1158/1535-7163.MCT-05-0181

  • Article
    Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons
    Hiroshi Y. Yamada and Gary J. Gorbsky
    Mol Cancer Ther January 1 2006 5 (1) 29-38; DOI:10.1158/1535-7163.MCT-05-0126

  • Article
    Modulation of nuclear factor E2-related factor 2–mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin
    Guoxiang Shen, Changjiang Xu, Rong Hu, Mohit R. Jain, Avantika Gopalkrishnan, Sujit Nair, Mou-Tuan Huang, Jefferson Y. Chan and Ah-Ng Tony Kong
    Mol Cancer Ther January 1 2006 5 (1) 39-51; DOI:10.1158/1535-7163.MCT-05-0293

  • Article
    Targeted delivery of methotrexate to epidermal growth factor receptor–positive brain tumors by means of cetuximab (IMC-C225) dendrimer bioconjugates
    Gong Wu, Rolf F. Barth, Weilian Yang, Shinji Kawabata, Liwen Zhang and Kari Green-Church
    Mol Cancer Ther January 1 2006 5 (1) 52-59; DOI:10.1158/1535-7163.MCT-05-0325

  • Article
    The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization
    Danhua Xiao, Atsuko Deguchi, Gregg G. Gundersen, Bert Oehlen, Lee Arnold and I. Bernard Weinstein
    Mol Cancer Ther January 1 2006 5 (1) 60-67; DOI:10.1158/1535-7163.MCT-05-0260

  • Article
    Enhancement of DNA topoisomerase I inhibitor–induced apoptosis by ursodeoxycholic acid
    Tadashi Ikegami, Yasushi Matsuzaki, Maryam Al Rashid, Susan Ceryak, Yining Zhang and Bernard Bouscarel
    Mol Cancer Ther January 1 2006 5 (1) 68-79; DOI:10.1158/1535-7163.MCT-05-0107

  • Article
    Improvement by solid dispersion of the bioavailability of KRN633, a selective inhibitor of VEGF receptor-2 tyrosine kinase, and identification of its potential therapeutic window
    Naoki Matsunaga, Kazuhide Nakamura, Atsushi Yamamoto, Eri Taguchi, Hiromi Tsunoda and Kazumi Takahashi
    Mol Cancer Ther January 1 2006 5 (1) 80-88; DOI:10.1158/1535-7163.MCT-05-0202

  • Article
    Antitumor efficacy of a urokinase activation–dependent anthrax toxin
    Birgitte Rønø, John Rømer, Shihui Liu, Thomas H. Bugge, Stephen H. Leppla and Paul E.G. Kristjansen
    Mol Cancer Ther January 1 2006 5 (1) 89-96; DOI:10.1158/1535-7163.MCT-05-0163

  • Article
    New enzyme for reductive cancer chemotherapy, YieF, and its improvement by directed evolution
    Yoram Barak, Stephen H. Thorne, David F. Ackerley, Susan V. Lynch, Christopher H. Contag and A. Matin
    Mol Cancer Ther January 1 2006 5 (1) 97-103; DOI:10.1158/1535-7163.MCT-05-0365

  • Article
    Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression levels
    Robert Wild, Krista Fager, Christine Flefleh, David Kan, Ivan Inigo, Stephen Castaneda, Feng (Roger) Luo, Amy Camuso, Kelly McGlinchey and William C. Rose
    Mol Cancer Ther January 1 2006 5 (1) 104-113; DOI:10.1158/1535-7163.MCT-05-0259

  • Article
    Novel human monoclonal antibodies to insulin-like growth factor (IGF)-II that potently inhibit the IGF receptor type I signal transduction function
    Yang Feng, Zhongyu Zhu, Xiaodong Xiao, Vidita Choudhry, J. Carl Barrett and Dimiter S. Dimitrov
    Mol Cancer Ther January 1 2006 5 (1) 114-120; DOI:10.1158/1535-7163.MCT-05-0252

  • Article
    Differential competitive resistance to methylating versus chloroethylating agents among five O6-alkylguanine DNA alkyltransferases in human hematopoietic cells
    Aparecida Maria Fontes, Brian M. Davis, Lance P. Encell, Karen Lingas, Dimas Tadeu Covas, Marco Antonio Zago, Lawrence A. Loeb, Anthony E. Pegg and Stanton L. Gerson
    Mol Cancer Ther January 1 2006 5 (1) 121-128; DOI:10.1158/1535-7163.MCT-05-0236

  • Article
    Novel angiogenic inhibitor DN-9693 that inhibits post-transcriptional induction of connective tissue growth factor (CTGF/CCN2) by vascular endothelial growth factor in human endothelial cells
    Seiji Kondo, Noriko Tanaka, Satoshi Kubota, Yoshiki Mukudai, Gen Yosimichi, Toshio Sugahara and Masaharu Takigawa
    Mol Cancer Ther January 1 2006 5 (1) 129-137; DOI:10.1158/1535-7163.MCT-05-0097

  • Article
    Flavopiridol disrupts STAT3/DNA interactions, attenuates STAT3-directed transcription, and combines with the Jak kinase inhibitor AG490 to achieve cytotoxic synergy
    Yean Kit Lee, Crescent R. Isham, Scott H. Kaufman and Keith C. Bible
    Mol Cancer Ther January 1 2006 5 (1) 138-148; DOI:10.1158/1535-7163.MCT-05-0235

  • Article
    Antitumor efficacy of CD137 ligation is maximized by the use of a CD137 single-chain Fv–expressing whole-cell tumor vaccine compared with CD137-specific monoclonal antibody infusion
    Hongtao Zhang, Keith L. Knutson, Karl Erik Hellstrom, Mary L. Disis and Ingegerd Hellstrom
    Mol Cancer Ther January 1 2006 5 (1) 149-155; DOI:10.1158/1535-7163.MCT-05-0206

  • Article
    Enhanced antiproliferative effects of alkoxyalkyl esters of cidofovir in human cervical cancer cells in vitro
    Karl Y. Hostetler, Steffney Rought, Kathy A. Aldern, Julissa Trahan, James R. Beadle and Jacques Corbeil
    Mol Cancer Ther January 1 2006 5 (1) 156-159; DOI:10.1158/1535-7163.MCT-05-0200

  • Article
    Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo
    Holly K. Koblish, Shuyuan Zhao, Carol F. Franks, Robert R. Donatelli, Rose M. Tominovich, Louis V. LaFrance, Kristi A. Leonard, Joan M. Gushue, Daniel J. Parks, Raul R. Calvo, Karen L. Milkiewicz, Juan José Marugán, Pierre Raboisson, Maxwell D. Cummings, Bruce L. Grasberger, Dana L. Johnson, Tianbao Lu, Christopher J. Molloy and Anna C. Maroney
    Mol Cancer Ther January 1 2006 5 (1) 160-169; DOI:10.1158/1535-7163.MCT-05-0199

  • Article
    Sensitization of TRAIL–resistant cells by inhibition of heat shock protein 90 with low-dose geldanamycin
    Yulin Ma, Vijayabaskar Lakshmikanthan, Ronald W. Lewis and M. Vijay Kumar
    Mol Cancer Ther January 1 2006 5 (1) 170-178; DOI:10.1158/1535-7163.MCT-05-0129

  • Article
    Silencing of survivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in human prostate cancer cells
    Francesco Paduano, Raffaella Villa, Marzia Pennati, Marco Folini, Mara Binda, Maria Grazia Daidone and Nadia Zaffaroni
    Mol Cancer Ther January 1 2006 5 (1) 179-186; DOI:10.1158/1535-7163.MCT-05-0132

  • Article
    Identification of magnetic resonance detectable metabolic changes associated with inhibition of phosphoinositide 3-kinase signaling in human breast cancer cells
    Mounia Beloueche-Babari, L. Elizabeth Jackson, Nada M.S. Al-Saffar, Suzanne A. Eccles, Florence I. Raynaud, Paul Workman, Martin O. Leach and Sabrina M. Ronen
    Mol Cancer Ther January 1 2006 5 (1) 187-196; DOI:10.1158/1535-7163.MCT-03-0220

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Molecular Cancer Therapeutics: 5 (1)
January 2006
Volume 5, Issue 1
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  • Restoration of p53 function for selective Fas-mediated apoptosis in human and rat glioma cells in vitro and in vivo by a p53 COOH-terminal peptide

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Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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