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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Article

Determination of the importance of the stereochemistry of psorospermin in topoisomerase II–induced alkylation of DNA and in vitro and in vivo biological activity

Ingrid M. Fellows, Michael Schwaebe, Thomas S. Dexheimer, Hariprasad Vankayalapati, Mary Gleason-Guzman, Jeffrey P. Whitten and Laurence H. Hurley
Ingrid M. Fellows
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Michael Schwaebe
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Thomas S. Dexheimer
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Hariprasad Vankayalapati
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Mary Gleason-Guzman
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Jeffrey P. Whitten
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Laurence H. Hurley
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DOI: 10.1158/1535-7163.MCT-05-0183 Published November 2005
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Article Information

Volume 4, Issue 11, pp. 1729-1739

DOI 
https://doi.org/10.1158/1535-7163.MCT-05-0183
PubMed 
16275994

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • September 13, 2005
  • June 7, 2005
  • August 25, 2005
  • Published first November 7, 2005.

Copyright & Usage 
American Association for Cancer Research

Author Information

  1. Ingrid M. Fellows1,
  2. Michael Schwaebe2,
  3. Thomas S. Dexheimer3,
  4. Hariprasad Vankayalapati3,
  5. Mary Gleason-Guzman3,
  6. Jeffrey P. Whitten2 and
  7. Laurence H. Hurley345
  1. 1The University of Texas at Austin, Austin, Texas; 2Cylene Pharmaceuticals, Inc., San Diego, California; and 3College of Pharmacy and 4Department of Chemistry, The University of Arizona and 5The Arizona Cancer Center, Tucson, Arizona
  1. Requests for reprints: Laurence H. Hurley, The Arizona Cancer Center, 1515 North Campbell Avenue, Tucson, AZ 85724. Phone: 520-626-5622; Fax: 520-626-5623. E-mail: hurley{at}pharmacy.arizona.edu
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Molecular Cancer Therapeutics: 4 (11)
November 2005
Volume 4, Issue 11
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Determination of the importance of the stereochemistry of psorospermin in topoisomerase II–induced alkylation of DNA and in vitro and in vivo biological activity
Ingrid M. Fellows, Michael Schwaebe, Thomas S. Dexheimer, Hariprasad Vankayalapati, Mary Gleason-Guzman, Jeffrey P. Whitten and Laurence H. Hurley
Mol Cancer Ther November 1 2005 (4) (11) 1729-1739; DOI: 10.1158/1535-7163.MCT-05-0183

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Determination of the importance of the stereochemistry of psorospermin in topoisomerase II–induced alkylation of DNA and in vitro and in vivo biological activity
Ingrid M. Fellows, Michael Schwaebe, Thomas S. Dexheimer, Hariprasad Vankayalapati, Mary Gleason-Guzman, Jeffrey P. Whitten and Laurence H. Hurley
Mol Cancer Ther November 1 2005 (4) (11) 1729-1739; DOI: 10.1158/1535-7163.MCT-05-0183
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Molecular Cancer Therapeutics
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