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Molecular Cancer Therapeutics
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F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd

Joel Morris, Donn G. Wishka, Omar D. Lopez, Vladimir Rudchenko, Guangfei Huang, Sierra N. Hoffman, Suzanne Borgel, Kyle Georgius, John Carter, Howard Stotler, Mark W. Kunkel, Jerry M. Collins, Melinda G. Hollingshead and Beverly A. Teicher
Joel Morris
1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
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  • For correspondence: joel.morris@nih.gov
Donn G. Wishka
1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
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Omar D. Lopez
1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
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  • ORCID record for Omar D. Lopez
Vladimir Rudchenko
2Alchem Laboratories Corporation, Alachua, Florida.
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Guangfei Huang
2Alchem Laboratories Corporation, Alachua, Florida.
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Sierra N. Hoffman
3Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland.
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Suzanne Borgel
3Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland.
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Kyle Georgius
3Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland.
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John Carter
3Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland.
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Howard Stotler
3Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland.
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Mark W. Kunkel
1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
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Jerry M. Collins
1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
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Melinda G. Hollingshead
1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
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  • ORCID record for Melinda G. Hollingshead
Beverly A. Teicher
1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
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DOI: 10.1158/1535-7163.MCT-20-0738 Published April 2021
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Article Information

Volume 20, Issue 4, pp. 625-631

DOI 
https://doi.org/10.1158/1535-7163.MCT-20-0738
PubMed 
33811149

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received August 27, 2020
  • Revision received November 5, 2020
  • Accepted January 8, 2021
  • Published first April 2, 2021.

Copyright & Usage 
©2021 American Association for Cancer Research.

Author Information

  1. Joel Morris1,*,
  2. Donn G. Wishka1,
  3. Omar D. Lopez1,
  4. Vladimir Rudchenko2,
  5. Guangfei Huang2,
  6. Sierra N. Hoffman3,
  7. Suzanne Borgel3,
  8. Kyle Georgius3,
  9. John Carter3,
  10. Howard Stotler3,
  11. Mark W. Kunkel1,
  12. Jerry M. Collins1,
  13. Melinda G. Hollingshead1, and
  14. Beverly A. Teicher1
  1. 1Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
  2. 2Alchem Laboratories Corporation, Alachua, Florida.
  3. 3Leidos Biomedical Laboratories, FNLCR, Frederick, Maryland.
  1. ↵*Corresponding Author:
    Joel Morris, National Cancer Institute, 9609 Medical Center Drive, Rockville, MD 20852. Phone: 240-276-5953; Fax: 240-276-7895; E-mail: joel.morris{at}nih.gov
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Molecular Cancer Therapeutics: 20 (4)
April 2021
Volume 20, Issue 4
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F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd
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F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd
Joel Morris, Donn G. Wishka, Omar D. Lopez, Vladimir Rudchenko, Guangfei Huang, Sierra N. Hoffman, Suzanne Borgel, Kyle Georgius, John Carter, Howard Stotler, Mark W. Kunkel, Jerry M. Collins, Melinda G. Hollingshead and Beverly A. Teicher
Mol Cancer Ther April 1 2021 (20) (4) 625-631; DOI: 10.1158/1535-7163.MCT-20-0738

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F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd
Joel Morris, Donn G. Wishka, Omar D. Lopez, Vladimir Rudchenko, Guangfei Huang, Sierra N. Hoffman, Suzanne Borgel, Kyle Georgius, John Carter, Howard Stotler, Mark W. Kunkel, Jerry M. Collins, Melinda G. Hollingshead and Beverly A. Teicher
Mol Cancer Ther April 1 2021 (20) (4) 625-631; DOI: 10.1158/1535-7163.MCT-20-0738
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