Table of Contents

Article

• Article

  DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer

  Adam Kashishian, Heather Douangpanya, Darcey Clark, Stephen T. Schlachter, C. Todd Eary, Justin G. Schiro, Hongmei Huang, Larry E. Burgess, Edward A. Kesicki and James Halbrook

  Mol Cancer Ther December 1 2003 2 (12) 1257-1264;

  
  
• Article

  Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4-amino-3-methylphenyl]-5-fluoro-benzothiazole: A potential surrogate marker for patient sensitivity

  Curtis D. Hose, Melinda Hollingshead, Edward A. Sausville and Anne Monks

  Mol Cancer Ther December 1 2003 2 (12) 1265-1272;

  
  
• Article

  Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells

  Roberto R. Rosato, Jorge A. Almenara, Yun Dai and Steven Grant

  Mol Cancer Ther December 1 2003 2 (12) 1273-1284;

  
  
• Article

  Nitric oxide does not mediate but inhibits transformation and tumor phenotype

  Arindam Dhar, June M. Brindley, Cristi Stark, Michael L. Citro, Larry K. Keefer and Nancy H. Colburn

  Mol Cancer Ther December 1 2003 2 (12) 1285-1293;

  
  
• Article

  Inhibition of tumor growth by a novel approach: In situ allicin generation using targeted alliinase delivery

  Talia Miron, Marina Mironchik, David Mirelman, Meir Wilchek and Aharon Rabinkov

  Mol Cancer Ther December 1 2003 2 (12) 1295-1301;

  
  
• Article

  Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation

  Stéphane Honore, Kathy Kamath, Diane Braguer, Leslie Wilson, Claudette Briand and Mary Ann Jordan

  Mol Cancer Ther December 1 2003 2 (12) 1303-1311;

  
  
• Article

  E1A gene therapy inhibits angiogenesis in a Ewing's sarcoma animal model

  Zhichao Zhou, Rong-Rong Zhou, Hui Guan, Corazon D. Bucana and Eugenie S. Kleinerman

  Mol Cancer Ther December 1 2003 2 (12) 1313-1319;

  
  
• Article

  Hematopoietic expression of O⁶-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O⁶-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea

  Emiko L. Kreklau, Karen E. Pollok, Barbara J. Bailey, Naili Liu, Jennifer R. Hartwell, David A. Williams and Leonard C. Erickson

  Mol Cancer Ther December 1 2003 2 (12) 1321-1329;

  
  
• Article

  Antitumor activity of the novel melphalan containing tripeptide J3 (l-prolyl-l-melphalanyl-p-l-fluorophenylalanine ethyl ester): Comparison with its m-l-sarcolysin analogue P2

  Joachim Gullbo, Charlotta Wallinder, Marcus Tullberg, Henrik Lövborg, Hans Ehrsson, Rolf Lewensohn, Peter Nygren, Kristina Luthman and Rolf Larsson

  Mol Cancer Ther December 1 2003 2 (12) 1331-1339;

  
  
• Article

  Targeted delivery of human pro-apoptotic enzymes to tumor cells: In vitro studies describing a novel class of recombinant highly cytotoxic agents

  Yuying Liu, Lawrence H. Cheung, Walter N. Hittelman and Michael G. Rosenblum

  Mol Cancer Ther December 1 2003 2 (12) 1341-1350;

  
  
• Article

  Genetic polymorphism at the 5′ regulatory region of multidrug resistance 1 (MDR1) and its association with interindividual variation of expression level in the colon

  Shuichi Taniguchi, Yasushi Mochida, Takeshi Uchiumi, Tomoko Tahira, Kenshi Hayashi, Koichi Takagi, Mitsuo Shimada, Yoshihiko Maehara, Hiroyuki Kuwano, Suminori Kono, Hitoo Nakano, Michihiko Kuwano and Morimasa Wada

  Mol Cancer Ther December 1 2003 2 (12) 1351-1359;

  
  
• Article

  Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy

  Ramzi M. Mohammad, Ayad Al-Katib, Amro Aboukameel, Daniel R. Doerge, Fazlul Sarkar and Omer Kucuk

  Mol Cancer Ther December 1 2003 2 (12) 1361-1368;

  
  
• Article

  Phosphoproteomic fingerprinting of epidermal growth factor signaling and anticancer drug action in human tumor cells

  Yoon-Pin Lim, Lang-Shi Diong, Robert Qi, Brian J. Druker and Richard J. Epstein

  Mol Cancer Ther December 1 2003 2 (12) 1369-1377;