Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth

Francesca Trotta; Paola Avena; Adele Chimento; Vittoria Rago; Arianna De Luca; Sara Sculco; Marta C. Nocito; Rocco Malivindi; Francesco Fallo; Raffaele Pezzani; Catia Pilon; Francesco M. Lasorsa; Simona N. Barile; Luigi Palmieri; Antonio M. Lerario; Vincenzo Pezzi; Ivan Casaburi; Rosa Sirianni

doi:10.1158/1535-7163.MCT-19-1063

Cancer Biology and Translational Studies

Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth

Francesca Trotta, Paola Avena, Adele Chimento, Vittoria Rago, Arianna De Luca, Sara Sculco, Marta C. Nocito, Rocco Malivindi, Francesco Fallo, Raffaele Pezzani, Catia Pilon, Francesco M. Lasorsa, Simona N. Barile, Luigi Palmieri, Antonio M. Lerario, Vincenzo Pezzi, Ivan Casaburi and Rosa Sirianni

Francesca Trotta

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Paola Avena

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Adele Chimento

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Vittoria Rago

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Arianna De Luca

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Sara Sculco

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Marta C. Nocito

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Rocco Malivindi

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Francesco Fallo

2Department of Medical and Surgical Sciences, University of Padua, Padua, Italy.

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Raffaele Pezzani

2Department of Medical and Surgical Sciences, University of Padua, Padua, Italy.

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Catia Pilon

2Department of Medical and Surgical Sciences, University of Padua, Padua, Italy.

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Francesco M. Lasorsa

3Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, and CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, Bari, Italy.

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Simona N. Barile

3Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, and CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, Bari, Italy.

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Luigi Palmieri

3Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, and CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, Bari, Italy.

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Antonio M. Lerario

4Departments of Molecular and Integrative Physiology and Internal Medicine, University of Michigan, Medical School, Ann Arbor, Michigan.

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Vincenzo Pezzi

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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For correspondence: rosa.sirianni@unical.it v.pezzi@unical.it

Ivan Casaburi

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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Rosa Sirianni

1Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy.

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ORCID record for Rosa Sirianni
For correspondence: rosa.sirianni@unical.it v.pezzi@unical.it

DOI: 10.1158/1535-7163.MCT-19-1063 Published September 2020

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September 2020
Volume 19, Issue 9

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Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth