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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Cancer Biology and Translational Studies

EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth

Sameer H. Issaq, Arnulfo Mendoza, Ria Kidner, Tracy I. Rosales, Damien Y. Duveau, Christine M. Heske, Jason M. Rohde, Matthew B. Boxer, Craig J. Thomas, Ralph J. DeBerardinis and Lee J. Helman
Sameer H. Issaq
1Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland.
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  • For correspondence: issaqsh@mail.nih.gov
Arnulfo Mendoza
1Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland.
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Ria Kidner
1Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland.
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Tracy I. Rosales
2Children's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas.
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Damien Y. Duveau
3National Center for Advancing Translational Sciences, NIH, Rockville, Maryland.
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  • ORCID record for Damien Y. Duveau
Christine M. Heske
1Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland.
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Jason M. Rohde
3National Center for Advancing Translational Sciences, NIH, Rockville, Maryland.
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Matthew B. Boxer
3National Center for Advancing Translational Sciences, NIH, Rockville, Maryland.
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Craig J. Thomas
3National Center for Advancing Translational Sciences, NIH, Rockville, Maryland.
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Ralph J. DeBerardinis
2Children's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas.
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Lee J. Helman
1Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland.
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DOI: 10.1158/1535-7163.MCT-19-0748 Published July 2020
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Molecular Cancer Therapeutics: 19 (7)
July 2020
Volume 19, Issue 7
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EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth
Sameer H. Issaq, Arnulfo Mendoza, Ria Kidner, Tracy I. Rosales, Damien Y. Duveau, Christine M. Heske, Jason M. Rohde, Matthew B. Boxer, Craig J. Thomas, Ralph J. DeBerardinis and Lee J. Helman
Mol Cancer Ther July 1 2020 (19) (7) 1520-1529; DOI: 10.1158/1535-7163.MCT-19-0748

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EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth
Sameer H. Issaq, Arnulfo Mendoza, Ria Kidner, Tracy I. Rosales, Damien Y. Duveau, Christine M. Heske, Jason M. Rohde, Matthew B. Boxer, Craig J. Thomas, Ralph J. DeBerardinis and Lee J. Helman
Mol Cancer Ther July 1 2020 (19) (7) 1520-1529; DOI: 10.1158/1535-7163.MCT-19-0748
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Molecular Cancer Therapeutics
eISSN: 1538-8514
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