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Molecular Cancer Therapeutics
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Companion Diagnostic, Pharmacogenomic, and Cancer Biomarkers

Early Assessment of Molecular Progression and Response by Whole-genome Circulating Tumor DNA in Advanced Solid Tumors

Andrew A. Davis, Wade T. Iams, David Chan, Michael S. Oh, Robert W. Lentz, Neil Peterman, Alex Robertson, Abhik Shah, Rohith Srivas, Timothy J. Wilson, Nicole J. Lambert, Peter S. George, Becky Wong, Haleigh W. Wood, Jason C. Close, Ayse Tezcan, Ken Nesmith, Haluk Tezcan and Young Kwang Chae
Andrew A. Davis
1Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
2Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois.
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Wade T. Iams
3Vanderbilt University Medical Center, Nashville, Tennessee.
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David Chan
4Cancer Care Associates TMPN, Redondo Beach, California.
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Michael S. Oh
1Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Robert W. Lentz
1Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Neil Peterman
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Alex Robertson
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Abhik Shah
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Rohith Srivas
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Timothy J. Wilson
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Nicole J. Lambert
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Peter S. George
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Becky Wong
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Haleigh W. Wood
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Jason C. Close
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Ayse Tezcan
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Ken Nesmith
5Lexent Bio, Inc., San Francisco and San Diego, California.
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Haluk Tezcan
5Lexent Bio, Inc., San Francisco and San Diego, California.
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  • For correspondence: young.chae@northwestern.edu htezcan@lexentbio.com
Young Kwang Chae
1Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
2Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois.
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  • For correspondence: young.chae@northwestern.edu htezcan@lexentbio.com
DOI: 10.1158/1535-7163.MCT-19-1060 Published July 2020
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Article Information

Volume 19, Issue 7, pp. 1486-1496

DOI 
https://doi.org/10.1158/1535-7163.MCT-19-1060
PubMed 
32371589

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received November 25, 2019
  • Revision received February 7, 2020
  • Accepted April 24, 2020
  • Published first May 5, 2020.

Article Versions

  • Previous version (May 5, 2020 - 07:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2020 American Association for Cancer Research.

Author Information

  1. Andrew A. Davis1,2,
  2. Wade T. Iams3,
  3. David Chan4,
  4. Michael S. Oh1,
  5. Robert W. Lentz1,
  6. Neil Peterman5,
  7. Alex Robertson5,
  8. Abhik Shah5,
  9. Rohith Srivas5,
  10. Timothy J. Wilson5,
  11. Nicole J. Lambert5,
  12. Peter S. George5,
  13. Becky Wong5,
  14. Haleigh W. Wood5,
  15. Jason C. Close5,
  16. Ayse Tezcan5,
  17. Ken Nesmith5,
  18. Haluk Tezcan5,*, and
  19. Young Kwang Chae1,2,*
  1. 1Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  2. 2Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois.
  3. 3Vanderbilt University Medical Center, Nashville, Tennessee.
  4. 4Cancer Care Associates TMPN, Redondo Beach, California.
  5. 5Lexent Bio, Inc., San Francisco and San Diego, California.
  1. ↵*Corresponding Authors:
    Young Kwang Chae, Northwestern University Feinberg School of Medicine, 645 N. Michigan Avenue, Suite 1006, Chicago, IL 60611. Phone: 312-926-4248; Fax: 312-695-0370; E-mail: young.chae{at}northwestern.edu; and Haluk Tezcan, 10355 Science Center Dr, #150; San Diego, CA 92121. E-mail: htezcan{at}lexentbio.com
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Molecular Cancer Therapeutics: 19 (7)
July 2020
Volume 19, Issue 7
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Early Assessment of Molecular Progression and Response by Whole-genome Circulating Tumor DNA in Advanced Solid Tumors
Andrew A. Davis, Wade T. Iams, David Chan, Michael S. Oh, Robert W. Lentz, Neil Peterman, Alex Robertson, Abhik Shah, Rohith Srivas, Timothy J. Wilson, Nicole J. Lambert, Peter S. George, Becky Wong, Haleigh W. Wood, Jason C. Close, Ayse Tezcan, Ken Nesmith, Haluk Tezcan and Young Kwang Chae
Mol Cancer Ther July 1 2020 (19) (7) 1486-1496; DOI: 10.1158/1535-7163.MCT-19-1060

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Early Assessment of Molecular Progression and Response by Whole-genome Circulating Tumor DNA in Advanced Solid Tumors
Andrew A. Davis, Wade T. Iams, David Chan, Michael S. Oh, Robert W. Lentz, Neil Peterman, Alex Robertson, Abhik Shah, Rohith Srivas, Timothy J. Wilson, Nicole J. Lambert, Peter S. George, Becky Wong, Haleigh W. Wood, Jason C. Close, Ayse Tezcan, Ken Nesmith, Haluk Tezcan and Young Kwang Chae
Mol Cancer Ther July 1 2020 (19) (7) 1486-1496; DOI: 10.1158/1535-7163.MCT-19-1060
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Molecular Cancer Therapeutics
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