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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Small Molecule Therapeutics

Combined Targeting of the BRD4–NUT–p300 Axis in NUT Midline Carcinoma by Dual Selective Bromodomain Inhibitor, NEO2734

Chevaun D. Morrison-Smith, Tatiana M. Knox, Ivona Filic, Kara M. Soroko, Benjamin K. Eschle, Margaret K. Wilkens, Prafulla C. Gokhale, Francis Giles, Andrew Griffin, Bill Brown, Geoffrey I. Shapiro, Beth E. Zucconi, Philip A. Cole, Madeleine E. Lemieux and Christopher A. French
Chevaun D. Morrison-Smith
1Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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Tatiana M. Knox
1Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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Ivona Filic
1Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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  • ORCID record for Ivona Filic
Kara M. Soroko
2Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
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Benjamin K. Eschle
2Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
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Margaret K. Wilkens
2Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
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Prafulla C. Gokhale
2Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
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Francis Giles
3Developmental Therapeutics Consortium, Chicago, Ilinois.
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  • ORCID record for Francis Giles
Andrew Griffin
4Praxis Precision Medicines, Cambridge, Massachusetts.
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Bill Brown
5Paraza Pharma Inc., Montreal, Quebec, Canada.
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Geoffrey I. Shapiro
6Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
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Beth E. Zucconi
7Department of Medicine, Division of Genetics, Brigham and Women's Hospital and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts.
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Philip A. Cole
7Department of Medicine, Division of Genetics, Brigham and Women's Hospital and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts.
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Madeleine E. Lemieux
8Bioinfo, Plantagenet, Ontario, Canada.
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Christopher A. French
1Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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  • ORCID record for Christopher A. French
  • For correspondence: cfrench@bwh.harvard.edu
DOI: 10.1158/1535-7163.MCT-20-0087 Published July 2020
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Molecular Cancer Therapeutics: 19 (7)
July 2020
Volume 19, Issue 7
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Combined Targeting of the BRD4–NUT–p300 Axis in NUT Midline Carcinoma by Dual Selective Bromodomain Inhibitor, NEO2734
Chevaun D. Morrison-Smith, Tatiana M. Knox, Ivona Filic, Kara M. Soroko, Benjamin K. Eschle, Margaret K. Wilkens, Prafulla C. Gokhale, Francis Giles, Andrew Griffin, Bill Brown, Geoffrey I. Shapiro, Beth E. Zucconi, Philip A. Cole, Madeleine E. Lemieux and Christopher A. French
Mol Cancer Ther July 1 2020 (19) (7) 1406-1414; DOI: 10.1158/1535-7163.MCT-20-0087

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Combined Targeting of the BRD4–NUT–p300 Axis in NUT Midline Carcinoma by Dual Selective Bromodomain Inhibitor, NEO2734
Chevaun D. Morrison-Smith, Tatiana M. Knox, Ivona Filic, Kara M. Soroko, Benjamin K. Eschle, Margaret K. Wilkens, Prafulla C. Gokhale, Francis Giles, Andrew Griffin, Bill Brown, Geoffrey I. Shapiro, Beth E. Zucconi, Philip A. Cole, Madeleine E. Lemieux and Christopher A. French
Mol Cancer Ther July 1 2020 (19) (7) 1406-1414; DOI: 10.1158/1535-7163.MCT-20-0087
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Molecular Cancer Therapeutics
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