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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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MCT First Disclosures

Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity

Helen Kotanides, Rose Marie Sattler, Maria B. Lebron, Carmine Carpenito, Juqun Shen, Jingxing Li, David Surguladze, Jaafar N. Haidar, Colleen Burns, Leyi Shen, Ivan Inigo, Anthony L. Pennello, Amelie Forest, Xinlei Chen, Darin Chin, Andreas Sonyi, Michael Topper, Lauren Boucher, Prachi Sharma, Yiwei Zhang, Douglas Burtrum, Ruslan D. Novosiadly, Dale L. Ludwig, Gregory D. Plowman and Michael Kalos
Helen Kotanides
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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  • For correspondence: helen.kotanides@lilly.com
Rose Marie Sattler
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Maria B. Lebron
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Carmine Carpenito
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Juqun Shen
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Jingxing Li
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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David Surguladze
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Jaafar N. Haidar
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Colleen Burns
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Leyi Shen
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Ivan Inigo
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Anthony L. Pennello
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Amelie Forest
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Xinlei Chen
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Darin Chin
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Andreas Sonyi
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Michael Topper
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Lauren Boucher
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Prachi Sharma
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Yiwei Zhang
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Douglas Burtrum
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Ruslan D. Novosiadly
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Dale L. Ludwig
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Gregory D. Plowman
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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Michael Kalos
Lilly Research Laboratories, Eli Lilly and Company, New York, New York.
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DOI: 10.1158/1535-7163.MCT-19-0893 Published April 2020
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Molecular Cancer Therapeutics: 19 (4)
April 2020
Volume 19, Issue 4
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Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity
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Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity
Helen Kotanides, Rose Marie Sattler, Maria B. Lebron, Carmine Carpenito, Juqun Shen, Jingxing Li, David Surguladze, Jaafar N. Haidar, Colleen Burns, Leyi Shen, Ivan Inigo, Anthony L. Pennello, Amelie Forest, Xinlei Chen, Darin Chin, Andreas Sonyi, Michael Topper, Lauren Boucher, Prachi Sharma, Yiwei Zhang, Douglas Burtrum, Ruslan D. Novosiadly, Dale L. Ludwig, Gregory D. Plowman and Michael Kalos
Mol Cancer Ther April 1 2020 (19) (4) 988-998; DOI: 10.1158/1535-7163.MCT-19-0893

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Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity
Helen Kotanides, Rose Marie Sattler, Maria B. Lebron, Carmine Carpenito, Juqun Shen, Jingxing Li, David Surguladze, Jaafar N. Haidar, Colleen Burns, Leyi Shen, Ivan Inigo, Anthony L. Pennello, Amelie Forest, Xinlei Chen, Darin Chin, Andreas Sonyi, Michael Topper, Lauren Boucher, Prachi Sharma, Yiwei Zhang, Douglas Burtrum, Ruslan D. Novosiadly, Dale L. Ludwig, Gregory D. Plowman and Michael Kalos
Mol Cancer Ther April 1 2020 (19) (4) 988-998; DOI: 10.1158/1535-7163.MCT-19-0893
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Molecular Cancer Therapeutics
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