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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Small Molecule Therapeutics

Aurora B Kinase Promotes CHIP-Dependent Degradation of HIF1α in Prostate Cancer Cells

Kuntal Biswas, Sukumar Sarkar, Neveen Said, David L. Brautigan and James M. Larner
Kuntal Biswas
1Department of Radiation Oncology, University of Virginia School of Medicine, Charlottesville, Virginia.
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Sukumar Sarkar
1Department of Radiation Oncology, University of Virginia School of Medicine, Charlottesville, Virginia.
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Neveen Said
1Department of Radiation Oncology, University of Virginia School of Medicine, Charlottesville, Virginia.
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David L. Brautigan
2Center for Cell Signaling, Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia.
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James M. Larner
1Department of Radiation Oncology, University of Virginia School of Medicine, Charlottesville, Virginia.
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  • For correspondence: JML2P@virginia.edu
DOI: 10.1158/1535-7163.MCT-19-0777 Published April 2020
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Article Information

Volume 19, Issue 4, pp. 1008-1017

DOI 
https://doi.org/10.1158/1535-7163.MCT-19-0777
PubMed 
31848297

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received August 8, 2019
  • Revision received September 25, 2019
  • Accepted December 12, 2019
  • Published first December 17, 2019.

Article Versions

  • Previous version (December 17, 2019 - 07:10).
  • Previous version (March 6, 2020 - 07:20).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Kuntal Biswas1,
  2. Sukumar Sarkar1,
  3. Neveen Said1,
  4. David L. Brautigan2, and
  5. James M. Larner1,*
  1. 1Department of Radiation Oncology, University of Virginia School of Medicine, Charlottesville, Virginia.
  2. 2Center for Cell Signaling, Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia.
  1. ↵*Corresponding Author:
    James M. Larner, University of Virginia School of Medicine, PO Box 800383, Charlottesville, VA 22908. Phone: 434-924-5564; Fax: 434-243-9789; E-mail: JML2P{at}virginia.edu
  • Current address for Neveen Said: Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC.

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Molecular Cancer Therapeutics: 19 (4)
April 2020
Volume 19, Issue 4
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Aurora B Kinase Promotes CHIP-Dependent Degradation of HIF1α in Prostate Cancer Cells
Kuntal Biswas, Sukumar Sarkar, Neveen Said, David L. Brautigan and James M. Larner
Mol Cancer Ther April 1 2020 (19) (4) 1008-1017; DOI: 10.1158/1535-7163.MCT-19-0777

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Aurora B Kinase Promotes CHIP-Dependent Degradation of HIF1α in Prostate Cancer Cells
Kuntal Biswas, Sukumar Sarkar, Neveen Said, David L. Brautigan and James M. Larner
Mol Cancer Ther April 1 2020 (19) (4) 1008-1017; DOI: 10.1158/1535-7163.MCT-19-0777
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Molecular Cancer Therapeutics
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