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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Cancer Biology and Translational Studies

Serum- and Glucocorticoid-inducible Kinase 1 is Essential for Osteoclastogenesis and Promotes Breast Cancer Bone Metastasis

Zheng Zhang, Qian Xu, Chao Song, Baoguo Mi, Honghua Zhang, Honglei Kang, Huiyong Liu, Yunlong Sun, Jia Wang, Zhuowei Lei, Hanfeng Guan and Feng Li
Zheng Zhang
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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  • ORCID record for Zheng Zhang
Qian Xu
2Department of Hematology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Chao Song
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Baoguo Mi
3Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, China.
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Honghua Zhang
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Honglei Kang
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Huiyong Liu
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Yunlong Sun
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Jia Wang
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Zhuowei Lei
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Hanfeng Guan
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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  • For correspondence: lifengmd@hust.edu.cn hguan@hust.edu.cn
Feng Li
1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
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  • For correspondence: lifengmd@hust.edu.cn hguan@hust.edu.cn
DOI: 10.1158/1535-7163.MCT-18-0783 Published February 2020
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ARTICLE USAGE: November 2019 to January 2021

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Total568624649

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Article Information

Volume 19, Issue 2, pp. 650-660

DOI 
https://doi.org/10.1158/1535-7163.MCT-18-0783
PubMed 
31694887

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received July 16, 2018
  • Revision received December 30, 2018
  • Accepted October 31, 2019
  • Published first November 6, 2019.

Article Versions

  • Previous version (November 6, 2019 - 07:32).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Zheng Zhang1,
  2. Qian Xu2,
  3. Chao Song1,
  4. Baoguo Mi3,
  5. Honghua Zhang1,
  6. Honglei Kang1,
  7. Huiyong Liu1,
  8. Yunlong Sun1,
  9. Jia Wang1,
  10. Zhuowei Lei1,
  11. Hanfeng Guan1,#,*, and
  12. Feng Li1,#,*
  1. 1Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
  2. 2Department of Hematology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
  3. 3Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, China.
  1. ↵*Corresponding Authors:
    Feng Li, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei 430000, P.R. China. Phone: 158-0271-1777; E-mail: lifengmd{at}hust.edu.cn; and Hanfeng Guan, hguan{at}hust.edu.cn
  1. ↵#H. Guan and F. Li contributed equally to this article.

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Molecular Cancer Therapeutics: 19 (2)
February 2020
Volume 19, Issue 2
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Serum- and Glucocorticoid-inducible Kinase 1 is Essential for Osteoclastogenesis and Promotes Breast Cancer Bone Metastasis
Zheng Zhang, Qian Xu, Chao Song, Baoguo Mi, Honghua Zhang, Honglei Kang, Huiyong Liu, Yunlong Sun, Jia Wang, Zhuowei Lei, Hanfeng Guan and Feng Li
Mol Cancer Ther February 1 2020 (19) (2) 650-660; DOI: 10.1158/1535-7163.MCT-18-0783

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Serum- and Glucocorticoid-inducible Kinase 1 is Essential for Osteoclastogenesis and Promotes Breast Cancer Bone Metastasis
Zheng Zhang, Qian Xu, Chao Song, Baoguo Mi, Honghua Zhang, Honglei Kang, Huiyong Liu, Yunlong Sun, Jia Wang, Zhuowei Lei, Hanfeng Guan and Feng Li
Mol Cancer Ther February 1 2020 (19) (2) 650-660; DOI: 10.1158/1535-7163.MCT-18-0783
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