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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Small Molecule Therapeutics

Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma

Branden A. Smeester, Garrett M. Draper, Nicholas J. Slipek, Alex T. Larsson, Natalie Stratton, Emily J. Pomeroy, Kelsie L. Becklin, Kenta Yamamoto, Kyle B. Williams, Kanut Laoharawee, Joseph J. Peterson, Juan E. Abrahante, Susan K. Rathe, Lauren J. Mills, Margaret R. Crosby, Wendy A. Hudson, Eric P. Rahrmann, David A. Largaespada and Branden S. Moriarity
Branden A. Smeester
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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  • ORCID record for Branden A. Smeester
Garrett M. Draper
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Nicholas J. Slipek
2Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
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  • ORCID record for Nicholas J. Slipek
Alex T. Larsson
2Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
3Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota.
4Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
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Natalie Stratton
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Emily J. Pomeroy
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Kelsie L. Becklin
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Kenta Yamamoto
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Kyle B. Williams
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Kanut Laoharawee
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Joseph J. Peterson
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Juan E. Abrahante
5UMII, University of Minnesota, Minneapolis, Minnesota.
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Susan K. Rathe
4Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
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Lauren J. Mills
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Margaret R. Crosby
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Wendy A. Hudson
6AHCSH Cancer Center, University of Minnesota, Minneapolis, Minnesota.
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Eric P. Rahrmann
7Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England.
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David A. Largaespada
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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Branden S. Moriarity
1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
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  • For correspondence: mori0164@umn.edu
DOI: 10.1158/1535-7163.MCT-20-0369 Published December 2020
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Molecular Cancer Therapeutics: 19 (12)
December 2020
Volume 19, Issue 12
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Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma
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Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma
Branden A. Smeester, Garrett M. Draper, Nicholas J. Slipek, Alex T. Larsson, Natalie Stratton, Emily J. Pomeroy, Kelsie L. Becklin, Kenta Yamamoto, Kyle B. Williams, Kanut Laoharawee, Joseph J. Peterson, Juan E. Abrahante, Susan K. Rathe, Lauren J. Mills, Margaret R. Crosby, Wendy A. Hudson, Eric P. Rahrmann, David A. Largaespada and Branden S. Moriarity
Mol Cancer Ther December 1 2020 (19) (12) 2528-2541; DOI: 10.1158/1535-7163.MCT-20-0369

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Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma
Branden A. Smeester, Garrett M. Draper, Nicholas J. Slipek, Alex T. Larsson, Natalie Stratton, Emily J. Pomeroy, Kelsie L. Becklin, Kenta Yamamoto, Kyle B. Williams, Kanut Laoharawee, Joseph J. Peterson, Juan E. Abrahante, Susan K. Rathe, Lauren J. Mills, Margaret R. Crosby, Wendy A. Hudson, Eric P. Rahrmann, David A. Largaespada and Branden S. Moriarity
Mol Cancer Ther December 1 2020 (19) (12) 2528-2541; DOI: 10.1158/1535-7163.MCT-20-0369
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Molecular Cancer Therapeutics
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