Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma

Branden A. Smeester; Garrett M. Draper; Nicholas J. Slipek; Alex T. Larsson; Natalie Stratton; Emily J. Pomeroy; Kelsie L. Becklin; Kenta Yamamoto; Kyle B. Williams; Kanut Laoharawee; Joseph J. Peterson; Juan E. Abrahante; Susan K. Rathe; Lauren J. Mills; Margaret R. Crosby; Wendy A. Hudson; Eric P. Rahrmann; David A. Largaespada; Branden S. Moriarity

doi:10.1158/1535-7163.MCT-20-0369

Small Molecule Therapeutics

Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma

Branden A. Smeester, Garrett M. Draper, Nicholas J. Slipek, Alex T. Larsson, Natalie Stratton, Emily J. Pomeroy, Kelsie L. Becklin, Kenta Yamamoto, Kyle B. Williams, Kanut Laoharawee, Joseph J. Peterson, Juan E. Abrahante, Susan K. Rathe, Lauren J. Mills, Margaret R. Crosby, Wendy A. Hudson, Eric P. Rahrmann, David A. Largaespada and Branden S. Moriarity

Branden A. Smeester

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Branden A. Smeester

Garrett M. Draper

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Garrett M. Draper

Nicholas J. Slipek

2Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Nicholas J. Slipek

Alex T. Larsson

2Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.

3Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota.

4Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Natalie Stratton

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Natalie Stratton

Emily J. Pomeroy

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Emily J. Pomeroy

Kelsie L. Becklin

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kenta Yamamoto

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kenta Yamamoto

Kyle B. Williams

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kanut Laoharawee

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Joseph J. Peterson

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Juan E. Abrahante

5UMII, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Juan E. Abrahante

Susan K. Rathe

4Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Lauren J. Mills

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Lauren J. Mills

Margaret R. Crosby

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Wendy A. Hudson

6AHCSH Cancer Center, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Eric P. Rahrmann

7Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Eric P. Rahrmann

David A. Largaespada

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Branden S. Moriarity

1Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: mori0164@umn.edu

DOI: 10.1158/1535-7163.MCT-20-0369 Published December 2020

Article
Figures & Data
Info & Metrics
PDF

Log in using your username and password

Username *

Password *

Forgot your user name or password?

Purchase access

You may purchase access to this article. This will require you to create an account if you don't already have one.

PreviousNext

December 2020
Volume 19, Issue 12

Table of Contents
Table of Contents (PDF)
About the Cover
Editorial Board (PDF)

Search for this keyword

View this article with LENS

Open full page PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for sharing this Molecular Cancer Therapeutics article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma

Message Subject (Your Name) has forwarded a page to you from Molecular Cancer Therapeutics

Message Body (Your Name) thought you would be interested in this article in Molecular Cancer Therapeutics.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma

Mol Cancer Ther December 1 2020 (19) (12) 2528-2541; DOI: 10.1158/1535-7163.MCT-20-0369

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K–AKT Signaling for the Treatment of Metastatic Osteosarcoma