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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Small Molecule Therapeutics

Inhibition of EZH2 Enhances the Antitumor Efficacy of Metformin in Prostate Cancer

Yifan Kong, Yanquan Zhang, Fengyi Mao, Zhuangzhuang Zhang, Zhiguo Li, Ruixin Wang, Jinghui Liu and Xiaoqi Liu
Yifan Kong
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
2Department of Animal Sciences, Purdue University, West Lafayette, Indiana.
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Yanquan Zhang
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
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Fengyi Mao
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
2Department of Animal Sciences, Purdue University, West Lafayette, Indiana.
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Zhuangzhuang Zhang
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
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Zhiguo Li
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
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Ruixin Wang
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
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Jinghui Liu
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
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Xiaoqi Liu
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
3Markey Cancer Center, University of Kentucky, Lexington, Kentucky.
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  • For correspondence: Xiaoqi.Liu@uky.edu
DOI: 10.1158/1535-7163.MCT-19-0874 Published December 2020
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Article Information

Volume 19, Issue 12, pp. 2490-2501

DOI 
https://doi.org/10.1158/1535-7163.MCT-19-0874
PubMed 
33024029

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received September 10, 2019
  • Revision received January 6, 2020
  • Accepted September 24, 2020
  • Published first October 6, 2020.

Article Versions

  • Previous version (October 6, 2020 - 08:48).
  • Previous version (November 16, 2020 - 07:47).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2020 American Association for Cancer Research.

Author Information

  1. Yifan Kong1,2,
  2. Yanquan Zhang1,
  3. Fengyi Mao1,2,
  4. Zhuangzhuang Zhang1,
  5. Zhiguo Li1,
  6. Ruixin Wang1,
  7. Jinghui Liu1, and
  8. Xiaoqi Liu1,3,*
  1. 1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.
  2. 2Department of Animal Sciences, Purdue University, West Lafayette, Indiana.
  3. 3Markey Cancer Center, University of Kentucky, Lexington, Kentucky.
  1. ↵*Corresponding Author:
    Xiaoqi Liu, University of Kentucky, Lexington, KY 40536. Phone: 859-257-3760; Fax: 859-323-1059; E-mail: Xiaoqi.Liu{at}uky.edu
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Molecular Cancer Therapeutics: 19 (12)
December 2020
Volume 19, Issue 12
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Inhibition of EZH2 Enhances the Antitumor Efficacy of Metformin in Prostate Cancer
Yifan Kong, Yanquan Zhang, Fengyi Mao, Zhuangzhuang Zhang, Zhiguo Li, Ruixin Wang, Jinghui Liu and Xiaoqi Liu
Mol Cancer Ther December 1 2020 (19) (12) 2490-2501; DOI: 10.1158/1535-7163.MCT-19-0874

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Inhibition of EZH2 Enhances the Antitumor Efficacy of Metformin in Prostate Cancer
Yifan Kong, Yanquan Zhang, Fengyi Mao, Zhuangzhuang Zhang, Zhiguo Li, Ruixin Wang, Jinghui Liu and Xiaoqi Liu
Mol Cancer Ther December 1 2020 (19) (12) 2490-2501; DOI: 10.1158/1535-7163.MCT-19-0874
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