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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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About the Cover

Cover image

Cover image expansion

Human papillomavirus (HPV) is detected in a vast majority of cervical cancers. For advanced cervical dysplasia (CIN3), co-infection with the human immunodeficiency virus (HIV) can result in more aggressive disease and disease recurrence. Various studies identified that HIV protease inhibitors (HIV-PI) can exert anti-tumor effects outside of its anti-viral activity. In this month's cover image, Qiu and colleagues demonstrate treating cervical cancer tumors with HIV-PIs increase expression of tissue inhibitors of metalloproteinase 3 (TIMP-3, shown in red) on cancer-associated fibroblasts. Read the full article on page 2476.

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Molecular Cancer Therapeutics: 19 (12)
December 2020
Volume 19, Issue 12
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Issue Highlights

  • Emerging CAR-T Cell Therapy for the Treatment of Triple-Negative Breast Cancer
  • Repurposing of a Thromboxane Receptor Inhibitor Based on a Novel Role in Metastasis Identified by Phenome-Wide Association Study
  • Glutaminase Inhibitors Induce Thiol-Mediated Oxidative Stress and Radiosensitization in Treatment-Resistant Cervical Cancers
  • An Antibody-Tumor Necrosis Factor Fusion Protein that Synergizes with Oxaliplatin for Treatment of Colorectal Cancer
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Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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