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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Small Molecule Therapeutics

Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage

Amrita Salvi, Chiraz Soumia M. Amrine, Julia R. Austin, KiAundra Kilpatrick, Angela Russo, Daniel Lantvit, Esther Calderon-Gierszal, Zachary Mattes, Cedric J. Pearce, Mark W. Grinstaff, Aaron H. Colby, Nicholas H. Oberlies and Joanna E. Burdette
Amrita Salvi
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
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  • ORCID record for Amrita Salvi
Chiraz Soumia M. Amrine
2Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina.
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Julia R. Austin
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
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KiAundra Kilpatrick
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
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Angela Russo
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
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Daniel Lantvit
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
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Esther Calderon-Gierszal
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
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Zachary Mattes
3Departments of Chemistry, Biomedical Engineering, and Medicine, Boston University, Boston, Massachusetts.
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Cedric J. Pearce
4Mycosynthetix Inc., Hillsborough, North Carolina.
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Mark W. Grinstaff
3Departments of Chemistry, Biomedical Engineering, and Medicine, Boston University, Boston, Massachusetts.
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Aaron H. Colby
3Departments of Chemistry, Biomedical Engineering, and Medicine, Boston University, Boston, Massachusetts.
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Nicholas H. Oberlies
2Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina.
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  • ORCID record for Nicholas H. Oberlies
Joanna E. Burdette
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
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  • For correspondence: joannab@uic.edu
DOI: 10.1158/1535-7163.MCT-19-0205 Published January 2020
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Article Information

Volume 19, Issue 1, pp. 89-100

DOI 
https://doi.org/10.1158/1535-7163.MCT-19-0205
PubMed 
31909733

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received February 28, 2019
  • Revision received June 6, 2019
  • Accepted September 9, 2019
  • Published first January 3, 2020.

Copyright & Usage 
©2020 American Association for Cancer Research.

Author Information

  1. Amrita Salvi1,
  2. Chiraz Soumia M. Amrine2,
  3. Julia R. Austin1,
  4. KiAundra Kilpatrick1,
  5. Angela Russo1,
  6. Daniel Lantvit1,
  7. Esther Calderon-Gierszal1,
  8. Zachary Mattes3,
  9. Cedric J. Pearce4,
  10. Mark W. Grinstaff3,
  11. Aaron H. Colby3,
  12. Nicholas H. Oberlies2, and
  13. Joanna E. Burdette1,*
  1. 1Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
  2. 2Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina.
  3. 3Departments of Chemistry, Biomedical Engineering, and Medicine, Boston University, Boston, Massachusetts.
  4. 4Mycosynthetix Inc., Hillsborough, North Carolina.
  1. ↵*Corresponding Author:
    Joanna E. Burdette, University of Illinois at Chicago, 900 S. Ashland Rm 3202, Chicago, IL 60607. Phone: 312-996-6153; Fax: 312-996-7107; E-mail: joannab{at}uic.edu
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Molecular Cancer Therapeutics: 19 (1)
January 2020
Volume 19, Issue 1
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Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage
Amrita Salvi, Chiraz Soumia M. Amrine, Julia R. Austin, KiAundra Kilpatrick, Angela Russo, Daniel Lantvit, Esther Calderon-Gierszal, Zachary Mattes, Cedric J. Pearce, Mark W. Grinstaff, Aaron H. Colby, Nicholas H. Oberlies and Joanna E. Burdette
Mol Cancer Ther January 1 2020 (19) (1) 89-100; DOI: 10.1158/1535-7163.MCT-19-0205

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Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage
Amrita Salvi, Chiraz Soumia M. Amrine, Julia R. Austin, KiAundra Kilpatrick, Angela Russo, Daniel Lantvit, Esther Calderon-Gierszal, Zachary Mattes, Cedric J. Pearce, Mark W. Grinstaff, Aaron H. Colby, Nicholas H. Oberlies and Joanna E. Burdette
Mol Cancer Ther January 1 2020 (19) (1) 89-100; DOI: 10.1158/1535-7163.MCT-19-0205
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